naa a22 4500 510799930 CHVBK 20180411083350.0 cr unu---uuuuu 180411e20130201xx s 000 0 eng 10.1007/s12028-012-9799-5 doi (NATIONALLICENCE)springer-10.1007/s12028-012-9799-5 Effect of Early Physiotherapy on Intracranial Pressure and Cerebral Perfusion Pressure [Elektronische Daten] [Christian Roth, Hubertus Stitz, Anas Kalhout, Jens Kleffmann, Wolfgang Deinsberger, Andreas Ferbert] Background: Physiotherapy plays an important role in the therapy of patients with acute cerebral diseases. Studies concerning the effects of physiotherapy on intracerebral pressure (ICP) and cerebral perfusion pressure (CPP) are, however, rare. Methods: An observational study was performed on critically ill patients who were receiving ICP measurements and who were treated with passive range of motion (PROM) on our neuro-intensive care unit. ICP, CPP, mean arterial pressure (MAP) and heart rate were recorded continuously every minute, beginning 15min before, during (26min) and 15min after treatment with PROM. Patients with mean ICP <15mmHg (Group 1) and patients with mean ICP ≥15mmHg (Group 2) before physiotherapy were analyzed separately. Results: Overall there were 84 patients (f:m=1:1) with 298 treatments units, 224 in Group 1 and 74 in Group 2, respectively. Mean ICP before treatment was 11.5±5.1mmHg, with a significant decrease of 1mmHg during therapy (p=2.0e-10). This was also true for Group 1 (baseline ICP 9.4±3.7mmHg, decrease of 0.7mmHg, p=3.8e-6) and Group 2 (baseline ICP 18.1±2.7mmHg, decrease of 2mmHg, p=3.7e-6). However, a persistent ICP reduction after therapy was seen only in Group 2. There were no significant differences between mean CPP and MAP comparing ICP before and after PROM in all groups. No adverse side effects of PROM were observed. Conclusions: Physiotherapy with PROM can be used safely in patients with acute neurological diseases, even if ICP is elevated before therapy. Springer Science+Business Media New York, 2012 Physiotherapy nationallicence Passive range of motion nationallicence Intracerebral pressure nationallicence ICP nationallicence Intensive care nationallicence Outcome nationallicence Roth Christian Department of Neurology, Klinikum Kassel, Mönchebergstraße 41-43, 34125, Kassel, Germany aut Stitz Hubertus Department of Physiotherapy, Klinikum Kassel, Kassel, Germany aut Kalhout Anas Department of Neurosurgery, Klinikum Kassel, Kassel, Germany aut Kleffmann Jens Department of Neurosurgery, Klinikum Kassel, Kassel, Germany aut Deinsberger Wolfgang Department of Neurosurgery, Klinikum Kassel, Kassel, Germany aut Ferbert Andreas Department of Neurology, Klinikum Kassel, Mönchebergstraße 41-43, 34125, Kassel, Germany aut Neurocritical Care Humana Press Inc 18/1(2013-02-01), 33-38 1541-6933 18:1<33 2013 18 12028 https://doi.org/10.1007/s12028-012-9799-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12028-012-9799-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roth Christian Department of Neurology, Klinikum Kassel, Mönchebergstraße 41-43, 34125, Kassel, Germany aut NATIONALLICENCE 700 1- Stitz Hubertus Department of Physiotherapy, Klinikum Kassel, Kassel, Germany aut NATIONALLICENCE 700 1- Kalhout Anas Department of Neurosurgery, Klinikum Kassel, Kassel, Germany aut NATIONALLICENCE 700 1- Kleffmann Jens Department of Neurosurgery, Klinikum Kassel, Kassel, Germany aut NATIONALLICENCE 700 1- Deinsberger Wolfgang Department of Neurosurgery, Klinikum Kassel, Kassel, Germany aut NATIONALLICENCE 700 1- Ferbert Andreas Department of Neurology, Klinikum Kassel, Mönchebergstraße 41-43, 34125, Kassel, Germany aut NATIONALLICENCE 773 0- Neurocritical Care Humana Press Inc 18/1(2013-02-01), 33-38 1541-6933 18:1<33 2013 18 12028 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer