naa a22 4500 51080022X CHVBK 20180411083352.0 cr unu---uuuuu 180411e20130401xx s 000 0 eng 10.1007/s12028-012-9789-7 doi (NATIONALLICENCE)springer-10.1007/s12028-012-9789-7 Causes and Outcomes of Persistent Vegetative State in a Chinese Versus American Referral Hospital [Elektronische Daten] [Farrah Mateen, Jing-Wen Niu, Shan Gao, Shun-Wei Li, Marco Carone, Eelco Wijdicks, Wei-Hai Xu] Objective: To compare the etiologies and clinical outcomes of patients in a persistent vegetative state (PVS) between a Chinese and US referral hospital. Methods: A retrospective, observational study at the Peking Union Medical College Hospital, Beijing, China and Johns Hopkins Hospital, Baltimore, USA (2001-2010) was performed. Results: There were 36 cases of PVS diagnosed. In Beijing, there were 19 cases: mean age 57years, range 3-86, (42%) female, with 37% of patients observed to survive more than 1year (range >1month to >28years, median >6months). Causes of PVS in Beijing were hemorrhagic stroke (n=4, 21%), ischemic stroke (n=2, 11%), cardiac arrest (n=5, 26%, including 4 with attempted cardiopulmonary resuscitation (CPR)), traumatic brain injury (n=3, 16%), and one each of mitochondrial encephalomyopathy, acute disseminated encephalomyelitis, Lennox Gastaut Syndrome, and epilepsy with craniopharyngioma (n=4, 21%). In Baltimore, there were 17 cases of PVS: mean age 43years, range 15-83, 59% female, with 41% observed to survive more than 1year (range >1month to >10years, median >3years). Causes of PVS in Baltimore were ischemic stroke (n=3, 18%), cardiac arrest (n=3, 18%, including one with attempted CPR), traumatic brain injury (n=3, 18%), neurodegenerative conditions (n=2, 12%), and hypoxic ischemic encephalopathy due to respiratory arrest (n=3, 18%), metabolic derangements (n=2, 12%), and meningitis (n=1, 6%). Conclusions: There may be a long survival period for patients with PVS, including in China where resource constraints exist for acute neurologic care. Stroke appears to be the most common underlying cause of PVS in Chinese patients, followed closely by cardiac arrest with attempted CPR. There appear to be more varied causes of PVS in the US referral hospital with a predominance of stroke, cardiac arrest, and traumatic brain injury. Springer Science+Business Media New York, 2012 Coma nationallicence Vegetative state nationallicence Cardiac arrest nationallicence China nationallicence Consciousness nationallicence Stroke nationallicence Mateen Farrah Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, Room E8527, 600 North Wolfe Street, 21205, Baltimore, MD, USA aut Niu Jing-Wen Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut Gao Shan Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut Li Shun-Wei Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut Carone Marco Division of Biostatistics, University of California at Berkeley, Berkeley, CA, USA aut Wijdicks Eelco Department of Neurology, Mayo Clinic, Rochester, MN, USA aut Xu Wei-Hai Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut Neurocritical Care Humana Press Inc 18/2(2013-04-01), 266-270 1541-6933 18:2<266 2013 18 12028 https://doi.org/10.1007/s12028-012-9789-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12028-012-9789-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mateen Farrah Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, Room E8527, 600 North Wolfe Street, 21205, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Niu Jing-Wen Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut NATIONALLICENCE 700 1- Gao Shan Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut NATIONALLICENCE 700 1- Li Shun-Wei Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut NATIONALLICENCE 700 1- Carone Marco Division of Biostatistics, University of California at Berkeley, Berkeley, CA, USA aut NATIONALLICENCE 700 1- Wijdicks Eelco Department of Neurology, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Xu Wei-Hai Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1, Beijing, China aut NATIONALLICENCE 773 0- Neurocritical Care Humana Press Inc 18/2(2013-04-01), 266-270 1541-6933 18:2<266 2013 18 12028 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer