naa a22 4500 510805566 CHVBK 20180411083416.0 cr unu---uuuuu 180411e20130101xx s 000 0 eng 10.1007/s12576-012-0233-8 doi (NATIONALLICENCE)springer-10.1007/s12576-012-0233-8 The association of ACE , ACTN3 and PPARA gene variants with strength phenotypes in middle school-age children [Elektronische Daten] [Ildus Ahmetov, Dmitry Gavrilov, Irina Astratenkova, Anastasiya Druzhevskaya, Alexandr Malinin, Elena Romanova, Victor Rogozkin] The aim of the study was to determine the association between ACE I/D, ACTN3 R577X and PPARA intron 7 G/C gene polymorphisms and strength-related traits in 457 middle school-age children (219 boys and 238 girls; aged 11±0.4years). The assessment of different phenotypes was conducted with a number of performance tests. Gene polymorphisms were determined by PCR. The ACE D allele was associated with high results of standing long-jump test in boys [II 148.3 (16.3) cm, ID 152.6 (19.6) cm, DD 158.2 (19.1) cm; P=0.037]. The ACTN3 R allele was associated with high results of performance tests in males only in combination with other genes (standing long-jump test: P=0.021; handgrip strength test: P<0.0001). Furthermore, the male carriers of the PPARA gene C allele demonstrated the best results of handgrip strength testing than GG homozygotes [GG 14.6 (4.0) kg, GC/CC 15.7 (4.3) kg; P=0.048]. Thus, the ACE, ACTN3 and PPARA gene variants are associated with strength-related traits in physically active middle school-age boys. The Physiological Society of Japan and Springer, 2012 Polymorphism nationallicence Gene nationallicence Genetics nationallicence Physiological development nationallicence Strength nationallicence Ahmetov Ildus Sport Technology Education Research Laboratory, Volga Region State Academy of Physical Culture, Sport and Tourism, 33, Universiade Village, 420138, Kazan, Russia aut Gavrilov Dmitry St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut Astratenkova Irina St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut Druzhevskaya Anastasiya St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut Malinin Alexandr St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut Romanova Elena St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut Rogozkin Victor St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut The Journal of Physiological Sciences Springer Japan 63/1(2013-01-01), 79-85 1880-6546 63:1<79 2013 63 12576 https://doi.org/10.1007/s12576-012-0233-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12576-012-0233-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ahmetov Ildus Sport Technology Education Research Laboratory, Volga Region State Academy of Physical Culture, Sport and Tourism, 33, Universiade Village, 420138, Kazan, Russia aut NATIONALLICENCE 700 1- Gavrilov Dmitry St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut NATIONALLICENCE 700 1- Astratenkova Irina St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut NATIONALLICENCE 700 1- Druzhevskaya Anastasiya St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut NATIONALLICENCE 700 1- Malinin Alexandr St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut NATIONALLICENCE 700 1- Romanova Elena St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut NATIONALLICENCE 700 1- Rogozkin Victor St Petersburg Research Institute of Physical Culture, 56 E, Ligovsky Ave, 191040, St Petersburg, Russia aut NATIONALLICENCE 773 0- The Journal of Physiological Sciences Springer Japan 63/1(2013-01-01), 79-85 1880-6546 63:1<79 2013 63 12576 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer