naa a22 4500 510805582 CHVBK 20180411083416.0 cr unu---uuuuu 180411e20131101xx s 000 0 eng 10.1007/s12576-013-0280-9 doi (NATIONALLICENCE)springer-10.1007/s12576-013-0280-9 Ace I/D polymorphism is associated with habitual physical activity in pubertal boys [Elektronische Daten] [Jarek Mäestu, Evelin Lätt, Triin Rääsk, Katrin Sak, Kariina Laas, Jaak Jürimäe, Toivo Jürimäe] We investigated the association between the angiotensin I-converting enzyme (ACE) gene insertion (I)/deletion (D) polymorphism and physical activity levels in boys at early pubertal stage (calendar age 12.04±0.77years). Body composition by DXA, pubertal stage and cardiovascular fitness on cycle ergometer were measured in addition to 7-day accelerometry. DNA was separated from the whole blood. Sedentary behaviour level was significantly lower in DD subjects compared to I allele carriers. A significant main effect of the D allele was found on total physical activity (F 1,256=5,453; p=0.020; η 2=0.021] and on light physical activity (F 1,256=4.74; p=0.030; η 2=0.018). Adding screen time as a covariate did not change ACE I/D polymorphism effect on total physical activity levels (F 2,256=3,326; p=0.041; η 2=0.025). Carriers of the D allele had significantly higher light physical activity (F 1,256=4,710; p=0.031; η 2=0.20), with screen time as covariate. In conclusion, ACE gene has a significant effect on sedentary, light and total physical activity levels in healthy 12-year-old boys. The Physiological Society of Japan and Springer Japan, 2013 Physical activity nationallicence Sedentary behaviour nationallicence ACE gene nationallicence Pubertal boys nationallicence Mäestu Jarek Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut Lätt Evelin Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut Rääsk Triin Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut Sak Katrin Asper Biotech, Vaksali 17a, 50410, Tartu, Estonia aut Laas Kariina Department of Psychology, Centre of Social, Behavioural and Health Sciences, University of Tartu, Tiigi 48, 50410, Tartu, Estonia aut Jürimäe Jaak Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut Jürimäe Toivo Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut The Journal of Physiological Sciences Springer Japan 63/6(2013-11-01), 427-434 1880-6546 63:6<427 2013 63 12576 https://doi.org/10.1007/s12576-013-0280-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12576-013-0280-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mäestu Jarek Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut NATIONALLICENCE 700 1- Lätt Evelin Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut NATIONALLICENCE 700 1- Rääsk Triin Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut NATIONALLICENCE 700 1- Sak Katrin Asper Biotech, Vaksali 17a, 50410, Tartu, Estonia aut NATIONALLICENCE 700 1- Laas Kariina Department of Psychology, Centre of Social, Behavioural and Health Sciences, University of Tartu, Tiigi 48, 50410, Tartu, Estonia aut NATIONALLICENCE 700 1- Jürimäe Jaak Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut NATIONALLICENCE 700 1- Jürimäe Toivo Department of Coaching Sciences, Centre of Social, Behavioural and Health Sciences, University of Tartu, Ravila 14a, 50411, Tartu, Estonia aut NATIONALLICENCE 773 0- The Journal of Physiological Sciences Springer Japan 63/6(2013-11-01), 427-434 1880-6546 63:6<427 2013 63 12576 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer