naa a22 4500 510805736 CHVBK 20180411083417.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s12576-013-0254-y doi (NATIONALLICENCE)springer-10.1007/s12576-013-0254-y Elastic properties of peripheral arteries in heart failure patients in comparison with normal subjects [Elektronische Daten] [Chengyu Liu, Dingchang Zheng, Lina Zhao, Peng Li, Bin Li, Alan Murray, Changchun Liu] Understanding the change in elastic properties of peripheral arteries in heart failure patients is of particular importance, especially when compared with normal subjects. To investigate factors associated with their difference, 40 normal subjects and 60 heart failure patients were studied. Electrocardiograms, carotid pulses and radial pulses were simultaneously recorded to determine carotid-radial pulse transit time (carotid-radial PTT), arm pulse wave velocity (PWV), and arterial volume distensibility. In comparison with normal subjects, carotid-radial PTT was lower by 8ms in heart failure patients, arm PWV higher by 1.4m/s, and peripheral arterial distensibility lower by 0.04% per mmHg (all significant, P<0.01). Peripheral arterial distensibility was significantly related to systolic blood pressure (SBP) and to left ventricular ejection fraction (LVEF) for heart failure patients (both P<0.001), but the relationship for the normal group was not statistically significant (both 0.05<P<0.1). Ageing had a significant inverse relationship with arterial distensibility in normal subjects (P<0.05), but not in heart failure patients (P=0.59). No subject in the normal group had an arterial distensibility lower than 0.1% per mmHg, in comparison with 28% (17/60) in the heart failure group. Peripheral arterial distensibility has been shown to be significantly lower in heart failure patients in comparison with normal subjects. High SBP and low LVEF were the main factors associated with low arterial distensibility in heart failure patients. The Physiological Society of Japan and Springer Japan, 2013 Arterial pressure nationallicence Arterial volume distensibility nationallicence Heart failure nationallicence Pulse wave velocity nationallicence Liu Chengyu School of Information Science and Engineering, Shandong University, 27 Shanda Nanlu, 250100, Jinan, China aut Zheng Dingchang Cardiovascular Physics and Engineering Research Group, Institute of Cellular Medicine, Newcastle University, Freeman Hospital, NE7 7DN, Newcastle upon Tyne, UK aut Zhao Lina Heng-Xin Inspection Technique Exploiture Center, 250012, Jinan, China aut Li Peng School of Control Science and Engineering, Shandong University, 250061, Jinan, China aut Li Bin Qilu Hospital, Shandong University, 250012, Jinan, China aut Murray Alan Cardiovascular Physics and Engineering Research Group, Institute of Cellular Medicine, Newcastle University, Freeman Hospital, NE7 7DN, Newcastle upon Tyne, UK aut Liu Changchun School of Control Science and Engineering, Shandong University, 250061, Jinan, China aut The Journal of Physiological Sciences Springer Japan 63/3(2013-05-01), 195-201 1880-6546 63:3<195 2013 63 12576 https://doi.org/10.1007/s12576-013-0254-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12576-013-0254-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Chengyu School of Information Science and Engineering, Shandong University, 27 Shanda Nanlu, 250100, Jinan, China aut NATIONALLICENCE 700 1- Zheng Dingchang Cardiovascular Physics and Engineering Research Group, Institute of Cellular Medicine, Newcastle University, Freeman Hospital, NE7 7DN, Newcastle upon Tyne, UK aut NATIONALLICENCE 700 1- Zhao Lina Heng-Xin Inspection Technique Exploiture Center, 250012, Jinan, China aut NATIONALLICENCE 700 1- Li Peng School of Control Science and Engineering, Shandong University, 250061, Jinan, China aut NATIONALLICENCE 700 1- Li Bin Qilu Hospital, Shandong University, 250012, Jinan, China aut NATIONALLICENCE 700 1- Murray Alan Cardiovascular Physics and Engineering Research Group, Institute of Cellular Medicine, Newcastle University, Freeman Hospital, NE7 7DN, Newcastle upon Tyne, UK aut NATIONALLICENCE 700 1- Liu Changchun School of Control Science and Engineering, Shandong University, 250061, Jinan, China aut NATIONALLICENCE 773 0- The Journal of Physiological Sciences Springer Japan 63/3(2013-05-01), 195-201 1880-6546 63:3<195 2013 63 12576 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer