naa a22 4500 510805787 CHVBK 20180411083417.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s12576-013-0267-6 doi (NATIONALLICENCE)springer-10.1007/s12576-013-0267-6 Dynamic exercise improves cognitive function in association with increased prefrontal oxygenation [Elektronische Daten] [Kana Endo, Kanji Matsukawa, Nan Liang, Chie Nakatsuka, Hirotsugu Tsuchimochi, Hitoshi Okamura, Takafumi Hamaoka] The Stroop test was performed before and after ergometer exercise for 15min at 20, 40, and 60% of maximum voluntary exercise (EXmax), in order to examine whether dynamic exercise is capable of improving cognitive function and whether the changes in regional cerebral blood flow of the prefrontal cortex are associated with the cognitive improvement. Subjects were asked to answer the displayed color of incongruent color words as quickly as possible. The total time period and the number of errors for the Stroop test were measured as an index of cognitive function. The concentrations of oxygenated-hemoglobin (Oxy-Hb) and deoxygenated-hemoglobin (Deoxy-Hb) in the cerebral prefrontal area were measured with near-infrared spectroscopy to determine the changes in regional cerebral blood flow. Ergometer exercise at 40% of EXmax, but not 20 and 60% of EXmax, shortened (P<0.05) the total time period for the Stroop test by 6.6±1.5% as compared to the time control. In contrast, the number of errors was not altered by exercise at any intensity. The Oxy-Hb in bilateral prefrontal cortices increased during the Stroop test, while the Deoxy-Hb in those areas was unchanged. Ergometer exercise at 40% of EXmax, but not at 20 and 60% of EXmax, significantly augmented the response in the prefrontal Oxy-Hb during the Stroop test. The magnitude of the increased prefrontal Oxy-Hb response tended to correlate with the reduction in total time period for the Stroop test. Thus, it is likely that ergometer exercise at moderate intensity for 15min may improve cognitive function through the increased neural activity in the prefrontal cortex. The Physiological Society of Japan and Springer Japan, 2013 Stroop test nationallicence Near-infrared spectroscopy nationallicence Prefrontal cortex nationallicence Dynamic exercise nationallicence Cognitive function nationallicence Endo Kana Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut Matsukawa Kanji Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut Liang Nan Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut Nakatsuka Chie Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut Tsuchimochi Hirotsugu Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut Okamura Hitoshi Department of Psychosocial Rehabilitation, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut Hamaoka Takafumi Faculty of Sport and Health Science, Ritsumeikan University, 1-1-1 Nojihigashi, 525-8577, Kusatsu, Shiga, Japan aut The Journal of Physiological Sciences Springer Japan 63/4(2013-07-01), 287-298 1880-6546 63:4<287 2013 63 12576 https://doi.org/10.1007/s12576-013-0267-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12576-013-0267-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Endo Kana Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Matsukawa Kanji Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Liang Nan Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Nakatsuka Chie Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Tsuchimochi Hirotsugu Department of Integrative Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Okamura Hitoshi Department of Psychosocial Rehabilitation, Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, 734-8551, Hiroshima, Japan aut NATIONALLICENCE 700 1- Hamaoka Takafumi Faculty of Sport and Health Science, Ritsumeikan University, 1-1-1 Nojihigashi, 525-8577, Kusatsu, Shiga, Japan aut NATIONALLICENCE 773 0- The Journal of Physiological Sciences Springer Japan 63/4(2013-07-01), 287-298 1880-6546 63:4<287 2013 63 12576 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer