naa a22 4500 510805876 CHVBK 20180411083418.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s12576-013-0274-7 doi (NATIONALLICENCE)springer-10.1007/s12576-013-0274-7 Are the precapillary sphincters and metarterioles universal components of the microcirculation? An historical review [Elektronische Daten] [Tatsuo Sakai, Yasue Hosoyamada] The microcirculation is a major topic in current physiology textbooks and is frequently explained with schematics including the precapillary sphincters and metarterioles. We re-evaluated the validity and applicability of the concepts precapillary sphincters and metarterioles by reviewing the historical context in which they were developed in physiology textbooks. The studies by Zweifach up until the 1950s revealed the unique features of the mesenteric microcirculation, illustrated with impressive schematics of the microcirculation with metarterioles and precapillary sphincters. Fulton, Guyton and other authors introduced or mimicked these schematics in their physiology textbooks as representative of the microcirculation in general. However, morphological and physiological studies have revealed that the microcirculation in the other organs and tissues contains no metarterioles or precapillary sphincters. The metarterioles and precapillary sphincters were not universal components of the microcirculation in general, but unique features of the mesenteric microcirculation. The Author(s), 2013 Microcirculation nationallicence Mesentery nationallicence Precapillary sphincter nationallicence Metarteriole nationallicence Physiology textbook nationallicence Sakai Tatsuo Department of Anatomy and Life Structure, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan aut Hosoyamada Yasue Department of Anatomy and Life Structure, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan aut The Journal of Physiological Sciences Springer Japan 63/5(2013-09-01), 319-331 1880-6546 63:5<319 2013 63 12576 https://doi.org/10.1007/s12576-013-0274-7 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12576-013-0274-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sakai Tatsuo Department of Anatomy and Life Structure, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan aut NATIONALLICENCE 700 1- Hosoyamada Yasue Department of Anatomy and Life Structure, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan aut NATIONALLICENCE 773 0- The Journal of Physiological Sciences Springer Japan 63/5(2013-09-01), 319-331 1880-6546 63:5<319 2013 63 12576 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer