naa a22 4500 510807119 CHVBK 20180411083423.0 cr unu---uuuuu 180411e20131101xx s 000 0 eng 10.1007/s11548-013-0831-9 doi (NATIONALLICENCE)springer-10.1007/s11548-013-0831-9 Accuracy analysis in MRI-guided robotic prostate biopsy [Elektronische Daten] [Helen Xu, Andras Lasso, Peter Guion, Axel Krieger, Aradhana Kaushal, Anurag Singh, Peter Pinto, Jonathan Coleman, Robert Grubb III, Jean-Baptiste Lattouf, Cynthia Menard, Louis Whitcomb, Gabor Fichtinger] Purpose: To assess retrospectively the clinical accuracy of an magnetic resonance imaging-guided robotic prostate biopsy system that has been used in the US National Cancer Institute for over 6 years. Methods: Series of 2D transverse volumetric MR image slices of the prostate both pre (high-resolution T2-weighted)- and post (low-resolution)- needle insertions were used to evaluate biopsy accuracy. A three-stage registration algorithm consisting of an initial two-step rigid registration followed by a B-spline deformable alignment was developed to capture prostate motion during biopsy. The target displacement (distance between planned and actual biopsy target), needle placement error (distance from planned biopsy target to needle trajectory), and biopsy error (distance from actual biopsy target to needle trajectory) were calculated as accuracy assessment. Results: A total of 90 biopsies from 24 patients were studied. The registrations were validated by checking prostate contour alignment using image overlay, and the results were accurate to within 2 mm. The mean target displacement, needle placement error, and clinical biopsy error were 5.2, 2.5, and 4.3 mm, respectively. Conclusion: The biopsy error reported suggests that quantitative imaging techniques for prostate registration and motion compensation may improve prostate biopsy targeting accuracy. CARS, 2013 Prostate biopsy nationallicence Accuracy validation nationallicence MRI-guidance nationallicence Image registration nationallicence Xu Helen Queen's University, Kingston, ON, Canada aut Lasso Andras Queen's University, Kingston, ON, Canada aut Guion Peter National Institutes of Health, Bethesda, MD, USA aut Krieger Axel Children's National Medical Center, Washington, DC, USA aut Kaushal Aradhana National Institutes of Health, Bethesda, MD, USA aut Singh Anurag Rosewell Park Cancer Institute, Buffalo, NY, USA aut Pinto Peter National Institutes of Health, Bethesda, MD, USA aut Coleman Jonathan Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Grubb III Robert Washington University in St. Louis, St. Louis, MO, USA aut Lattouf Jean-Baptiste Centre Hospitalier de L'Universite de Montreal, Montreal, QC, Canada aut Menard Cynthia Princess Margaret Hospital, Toronto, ON, Canada aut Whitcomb Louis Johns Hopkins University, Baltimore, MD, USA aut Fichtinger Gabor Queen's University, Kingston, ON, Canada aut International Journal of Computer Assisted Radiology and Surgery Springer Berlin Heidelberg 8/6(2013-11-01), 937-944 1861-6410 8:6<937 2013 8 11548 https://doi.org/10.1007/s11548-013-0831-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11548-013-0831-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Xu Helen Queen's University, Kingston, ON, Canada aut NATIONALLICENCE 700 1- Lasso Andras Queen's University, Kingston, ON, Canada aut NATIONALLICENCE 700 1- Guion Peter National Institutes of Health, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Krieger Axel Children's National Medical Center, Washington, DC, USA aut NATIONALLICENCE 700 1- Kaushal Aradhana National Institutes of Health, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Singh Anurag Rosewell Park Cancer Institute, Buffalo, NY, USA aut NATIONALLICENCE 700 1- Pinto Peter National Institutes of Health, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Coleman Jonathan Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Grubb III Robert Washington University in St. Louis, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Lattouf Jean-Baptiste Centre Hospitalier de L'Universite de Montreal, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Menard Cynthia Princess Margaret Hospital, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Whitcomb Louis Johns Hopkins University, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Fichtinger Gabor Queen's University, Kingston, ON, Canada aut NATIONALLICENCE 773 0- International Journal of Computer Assisted Radiology and Surgery Springer Berlin Heidelberg 8/6(2013-11-01), 937-944 1861-6410 8:6<937 2013 8 11548 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer