naa a22 4500 510808158 CHVBK 20180411083428.0 cr unu---uuuuu 180411e20130901xx s 000 0 eng 10.1007/s11548-012-0804-4 doi (NATIONALLICENCE)springer-10.1007/s11548-012-0804-4 Performance evaluation of a C-Arm CT perfusion phantom [Elektronische Daten] [Axel Boese, Sebastian Gugel, Steffen Serowy, Jonas Purmann, Georg Rose, Oliver Beuing, Martin Skalej, Yiannis Kyriakou, Yu Deuerling-Zheng] Purpose Brain perfusion measurement in stroke patients provides important information on the infarct area and state of involved tissue. Interventional C-Arm angiography systems can provide perfusion measurements. A CT perfusion phantom was developed for C-Arm perfusion imaging to test and evaluate this method and to aid in the design and validation of scan protocols. Methods A phantom test device was designed based on the anatomy of the human head. Four feeding arteries divided into sixteen sub-branches that lead into a sintered board simulating brain parenchyma. Perfusion measurements were performed using two conventional clinical CT scanners as the gold standard and with a C-Arm CT system to test and compare the implementations. The phantom's input parameters, contrast medium and flow properties were varied. A cerebral perfusion deficit was simulated by occlusion of a feeding artery tube. Results CT perfusion maps of the sintered board brain tissue surrogate were computed and qualitatively compared for both conventional CT and C-Arm CT systems. A characteristic flow pattern of the tissue board was identifiable in both modalities. The characteristic flow pattern of the resulting perfusion maps is reproducible. The calculated flow and volume were directly related. Conclusions A new CT perfusion phantom was developed and tested. This phantom is an appropriate model for CT-based tissue perfusion measurements in both conventional CT scanners and C-Arm CT scanners. The influence of input parameter changes can be visualized. Perfusion deficits after occlusion of a feeding artery are readily simulated and identified with CT. CARS, 2012 Phantom nationallicence Perfusion nationallicence CT nationallicence C-Arm CT nationallicence Imaging nationallicence Blood flow nationallicence Boese Axel Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut Gugel Sebastian Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut Serowy Steffen Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut Purmann Jonas Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut Rose Georg Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut Beuing Oliver Department of Neuroradiology, Otto-von-Guericke University, Magdeburg, Germany aut Skalej Martin Department of Neuroradiology, Otto-von-Guericke University, Magdeburg, Germany aut Kyriakou Yiannis Siemens AG, Healthcare Sector, Forchheim, Germany aut Deuerling-Zheng Yu Siemens AG, Healthcare Sector, Forchheim, Germany aut International Journal of Computer Assisted Radiology and Surgery Springer Berlin Heidelberg 8/5(2013-09-01), 799-807 1861-6410 8:5<799 2013 8 11548 https://doi.org/10.1007/s11548-012-0804-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11548-012-0804-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Boese Axel Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Gugel Sebastian Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Serowy Steffen Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Purmann Jonas Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Rose Georg Chair for Healthcare Telematics and Medical Engineering, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Beuing Oliver Department of Neuroradiology, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Skalej Martin Department of Neuroradiology, Otto-von-Guericke University, Magdeburg, Germany aut NATIONALLICENCE 700 1- Kyriakou Yiannis Siemens AG, Healthcare Sector, Forchheim, Germany aut NATIONALLICENCE 700 1- Deuerling-Zheng Yu Siemens AG, Healthcare Sector, Forchheim, Germany aut NATIONALLICENCE 773 0- International Journal of Computer Assisted Radiology and Surgery Springer Berlin Heidelberg 8/5(2013-09-01), 799-807 1861-6410 8:5<799 2013 8 11548 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer