naa a22 4500 51081347X CHVBK 20180411083453.0 cr unu---uuuuu 180411e20130201xx s 000 0 eng 10.1007/s12328-012-0347-9 doi (NATIONALLICENCE)springer-10.1007/s12328-012-0347-9 Hepatectomy in a hepatocellular carcinoma case with Dubin-Johnson syndrome and indocyanine green excretory defect [Elektronische Daten] [Hideki Aoki, Toshiaki Morihiro, Takashi Arata, Nobuhiko Kanaya, Shou Takeda, Takayuki Ninomiya, Masayuki Seita, Kou Katsuda, Kohji Tanakaya, Hitoshi Takeuchi] A 77-year-old male patient with history of jaundice was referred to our hospital for treatment of hepatocellular carcinoma (HCC). He was found to have Dubin-Johnson syndrome (DJS), a clinical feature of constitutional jaundice with conjugated hyperbilirubinemia, and indocyanine green (ICG) excretory defect, both of which are rare conditions. Total bilirubin was 5.1mg/dl and ICG retention at 15min (ICGR15) (77.1%). Converted ICGR15 from GSA scintigraphy was 15.9%. Resection of the medial segment and ventral region of the anterior segment of the liver as well as cholecystectomy were performed. The background of the liver tissue was blackish yellow and consistent with DJS and chronic hepatitis. Although total bilirubin level increased to 8.2mg/dl on the 2nd postoperative day, the patient ultimately recovered and he was discharged on the 14th day. His 1- and 2-year medical checkups indicated recurrence of HCC. He underwent transarterial chemoembolization and is presently doing well 39months after surgery. We report here on evaluation and treatment of patients with such disorders. Springer Japan, 2012 Dubin-Johnson syndrome nationallicence Indocyanine green excretory defect nationallicence Hepatocellular carcinoma nationallicence GSA liver scintigraphy nationallicence Aoki Hideki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Morihiro Toshiaki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Arata Takashi National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Kanaya Nobuhiko National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Takeda Shou National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Ninomiya Takayuki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Seita Masayuki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Katsuda Kou National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Tanakaya Kohji National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Takeuchi Hitoshi National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut Clinical Journal of Gastroenterology Springer Japan 6/1(2013-02-01), 69-74 1865-7257 6:1<69 2013 6 12328 https://doi.org/10.1007/s12328-012-0347-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12328-012-0347-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Aoki Hideki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Morihiro Toshiaki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Arata Takashi National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Kanaya Nobuhiko National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Takeda Shou National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Ninomiya Takayuki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Seita Masayuki National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Katsuda Kou National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Tanakaya Kohji National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 700 1- Takeuchi Hitoshi National Hospital Iwakuni Clinical Center, Department of Surgery, 2-5-1 Kuroiso-machi, 740-8510, Iwakuni-shi, Yamaguchi, Japan aut NATIONALLICENCE 773 0- Clinical Journal of Gastroenterology Springer Japan 6/1(2013-02-01), 69-74 1865-7257 6:1<69 2013 6 12328 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer