naa a22 4500 510813909 CHVBK 20180411083455.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s12328-013-0383-0 doi (NATIONALLICENCE)springer-10.1007/s12328-013-0383-0 Extensive 0-IIc (undifferentiated carcinoma) lesion around a gastric adenoma: a case report [Elektronische Daten] [Yusuke Horiuchi, Junko Fujisaki, Tomoki Shimizu, Hirotaka Ishikawa, Yasumasa Matsuo, Natsuko Yoshizawa, Takanori Suganuma, Kiyohisa Dan, Masami Omae, Akiyoshi Ishiyama, Toshiaki Hirasawa, Yorimasa Yamamoto, Tomohiro Tsuchida, Etsuo Hoshino, Masahiro Igarashi, Naoki Hiki, Toshiharu Yamaguchi, Toshifusa Nakajima, Hiroshi Takahashi] A 73-year-old woman underwent esophagogastroduodenoscopy (EGD) at a local hospital, which revealed a flat elevated lesion, approximately 15mm in diameter, in the posterior wall of the lower gastric body. At our hospital, a repeat EGD and biopsy led to a diagnosis of moderately dysplastic adenoma. The patient requested endoscopic submucosal dissection (ESD). Histopathology revealed a gastric adenoma with negativity for tumor at the vertical margin; however, the horizontal margin was positive for cancer with an undifferentiated carcinoma surrounding the adenoma. EGD was repeated, and a discolored area was found around the ESD scar. Biopsy revealed an undifferentiated carcinoma. Laparoscopic distal gastrectomy was performed, and postoperative histopathology also revealed an undifferentiated carcinoma (50mm in diameter) surrounding the ESD scar; this lesion was an undifferentiated adenocarcinoma that was colocalized with and spread out to surround the original adenoma. This case is important for consideration of the pattern of development and progression of superficial spreading gastric cancer. Springer Japan, 2013 Adenoma nationallicence Undifferentiated carcinoma nationallicence Gastric cancer nationallicence Horiuchi Yusuke Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Fujisaki Junko Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Shimizu Tomoki Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Ishikawa Hirotaka Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Matsuo Yasumasa Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Yoshizawa Natsuko Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Suganuma Takanori Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Dan Kiyohisa Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Omae Masami Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Ishiyama Akiyoshi Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Hirasawa Toshiaki Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Yamamoto Yorimasa Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Tsuchida Tomohiro Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Hoshino Etsuo Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Igarashi Masahiro Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut Hiki Naoki Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan aut Yamaguchi Toshiharu Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan aut Nakajima Toshifusa Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan aut Takahashi Hiroshi Department of Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Japan aut Clinical Journal of Gastroenterology Springer Japan 6/3(2013-06-01), 221-225 1865-7257 6:3<221 2013 6 12328 https://doi.org/10.1007/s12328-013-0383-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12328-013-0383-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Horiuchi Yusuke Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Fujisaki Junko Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Shimizu Tomoki Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Ishikawa Hirotaka Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Matsuo Yasumasa Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Yoshizawa Natsuko Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Suganuma Takanori Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Dan Kiyohisa Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Omae Masami Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Ishiyama Akiyoshi Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Hirasawa Toshiaki Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamamoto Yorimasa Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsuchida Tomohiro Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Hoshino Etsuo Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Igarashi Masahiro Department of Gastroenterology, Cancer Institute Hospital, 3-10-6 Ariake, Koto-ku, 135-8550, Tokyo, Japan aut NATIONALLICENCE 700 1- Hiki Naoki Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamaguchi Toshiharu Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Nakajima Toshifusa Department of Gastrointestinal Surgery, Cancer Institute Hospital, Tokyo, Japan aut NATIONALLICENCE 700 1- Takahashi Hiroshi Department of Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Japan aut NATIONALLICENCE 773 0- Clinical Journal of Gastroenterology Springer Japan 6/3(2013-06-01), 221-225 1865-7257 6:3<221 2013 6 12328 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer