naa a22 4500 510813984 CHVBK 20180411083456.0 cr unu---uuuuu 180411e20130801xx s 000 0 eng 10.1007/s12328-013-0403-0 doi (NATIONALLICENCE)springer-10.1007/s12328-013-0403-0 Primary gastric synovial sarcoma: molecular diagnosis and prediction of prognosis [Elektronische Daten] [Kohsuke Kamata, Ryuichi Wada, Nobuhisa Yajima, Mitsuhiro Sawada, Haruki Wakasa, Soroku Yagihashi] A 42-year-old Japanese woman complained of upper abdominal pain. Endoscopic examination demonstrated an elevated lesion in the body of the stomach, and a biopsy specimen demonstrated proliferation of atypical spindle cells. She underwent partial gastrectomy; the resected tumor measured 3.5×2.8×1.2cm in size. Histological examination disclosed the haphazard proliferation of spindle cells in the mucosa mixed with less prominent epithelioglandular component. The spindle cells were positive for cytokeratin, vimentin, EMA and CD99, but not for KIT, DOG1, desmin or S100. Reverse transcription-polymerase chain reaction using paraffin sections amplified a SYT-SSX1 chimera transcript. A diagnosis of synovial sarcoma was made. There has been no sign of recurrence or metastasis for 6years after the operation. Synovial sarcoma in the stomach is very rare. Since differential diagnosis of synovial sarcoma from carcinosarcoma and mesenchymal tumors is critical for the treatment and prediction of prognosis, accurate diagnosis with molecular analysis is essential. Springer Japan, 2013 Synovial sarcoma nationallicence Carcinosarcoma nationallicence Stomach nationallicence CD99 nationallicence SYT - SSX nationallicence RT-PCR nationallicence Kamata Kohsuke Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut Wada Ryuichi Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut Yajima Nobuhisa Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut Sawada Mitsuhiro Surgery, EST Clinic, Hirosaki, Japan aut Wakasa Haruki Diagnostic Pathology Japan, Inc., Sendai, Japan aut Yagihashi Soroku Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut Clinical Journal of Gastroenterology Springer Japan 6/4(2013-08-01), 303-308 1865-7257 6:4<303 2013 6 12328 https://doi.org/10.1007/s12328-013-0403-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12328-013-0403-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kamata Kohsuke Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut NATIONALLICENCE 700 1- Wada Ryuichi Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut NATIONALLICENCE 700 1- Yajima Nobuhisa Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut NATIONALLICENCE 700 1- Sawada Mitsuhiro Surgery, EST Clinic, Hirosaki, Japan aut NATIONALLICENCE 700 1- Wakasa Haruki Diagnostic Pathology Japan, Inc., Sendai, Japan aut NATIONALLICENCE 700 1- Yagihashi Soroku Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, 036-8562, Hirosaki, Japan aut NATIONALLICENCE 773 0- Clinical Journal of Gastroenterology Springer Japan 6/4(2013-08-01), 303-308 1865-7257 6:4<303 2013 6 12328 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer