naa a22 4500 510814026 CHVBK 20180411083456.0 cr unu---uuuuu 180411e20130801xx s 000 0 eng 10.1007/s12328-013-0397-7 doi (NATIONALLICENCE)springer-10.1007/s12328-013-0397-7 A case of lymphomatoid gastropathy: a self-limited pseudomalignant natural killer (NK)-cell proliferative disease mimicking NK/T-cell lymphomas [Elektronische Daten] [Yoko Ishibashi, Emi Matsuzono, Fumiaki Yokoyama, Yoshihito Ohara, Nozomu Sugai, Hideyuki Seki, Atsuhiko Miura, Jun Fujita, Junichi Suzuki, Takashi Fujisawa, Akira Suzuki, Yutaka Hatanaka] Natural killer (NK)/T-cell lymphomas exhibit aggressive tumor behavior and have a poor prognosis. Recently, self-limited pseudomalignant NK-cell proliferative disorders of the stomach mimicking NK/T-cell lymphomas have been recognized. We report a rare case of lymphomatoid gastropathy in a 71-year-old female. The patient underwent esophagogastroduodenoscopy (EGD) because of slight epigastric discomfort which revealed a 10-mm, reddish, flat elevation with erosion on the posterior wall of the lower gastric body. Histological examination of biopsy specimens showed atypical NK/T cell infiltration with cytoplasmic CD3+, CD4−, CD5−, CD7+, CD8−, CD16−, CD20−, CD56+, CD68−, CD117−, MPO−, TIA1+, and granzyme B+. Epstein−Barr virus-encoded RNA in situ hybridization was negative. Three months later, repeated endoscopic examination surprisingly revealed spontaneous regression of the lesion without any treatment. It is important that endoscopists consider this rare entity in the differential diagnosis, and excessive treatment should be avoided. Springer Japan, 2013 Helicobacter pylori nationallicence Lymphomatoid gastropathy nationallicence NK-cell enteropathy nationallicence NK/T-cell lymphoma nasal type nationallicence Stomach nationallicence Ishibashi Yoko Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Matsuzono Emi Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Yokoyama Fumiaki Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Ohara Yoshihito Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Sugai Nozomu Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Seki Hideyuki Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Miura Atsuhiko Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Fujita Jun Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Suzuki Junichi Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut Fujisawa Takashi Department of Pathology, KKR Sapporo Medical Center, Sapporo, Japan aut Suzuki Akira Department of Pathology, KKR Sapporo Medical Center, Sapporo, Japan aut Hatanaka Yutaka Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan aut Clinical Journal of Gastroenterology Springer Japan 6/4(2013-08-01), 287-290 1865-7257 6:4<287 2013 6 12328 https://doi.org/10.1007/s12328-013-0397-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12328-013-0397-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ishibashi Yoko Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Matsuzono Emi Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Yokoyama Fumiaki Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Ohara Yoshihito Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Sugai Nozomu Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Seki Hideyuki Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Miura Atsuhiko Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Fujita Jun Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Suzuki Junichi Department of Gastroenterology, KKR Sapporo Medical Center, 3-40, 1-jo, 6-chome, Toyohira-ku, 062-0931, Sapporo, Japan aut NATIONALLICENCE 700 1- Fujisawa Takashi Department of Pathology, KKR Sapporo Medical Center, Sapporo, Japan aut NATIONALLICENCE 700 1- Suzuki Akira Department of Pathology, KKR Sapporo Medical Center, Sapporo, Japan aut NATIONALLICENCE 700 1- Hatanaka Yutaka Department of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan aut NATIONALLICENCE 773 0- Clinical Journal of Gastroenterology Springer Japan 6/4(2013-08-01), 287-290 1865-7257 6:4<287 2013 6 12328 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer