naa a22 4500 510814093 CHVBK 20180411083456.0 cr unu---uuuuu 180411e20130801xx s 000 0 eng 10.1007/s12328-013-0405-y doi (NATIONALLICENCE)springer-10.1007/s12328-013-0405-y Mediastinal histoplasmosis presenting as dysphagia: a case report with literature review [Elektronische Daten] [Dhara Chaudhari, Jason Mckinney, Doris Hubbs, Mark Young] Histoplasmosis is an endemic infection of the Ohio and Mississippi River valleys. Clinical presentation of infection in immunocompetent hosts ranges from asymptomatic to minor flu-like symptoms; however, disseminated infection can occur in immunocompromised patients. Esophageal involvement in the form of dysphagia secondary to mediastinal histoplasmosis is rarely reported in the literature. We present a young female who complained of dysphagia and was found to have an esophageal stricture on barium esophagogram. Endoscopy revealed a submucosal nodule stricture situated 29cm from the incisors. She underwent thoracotomy for lymph node removal. Histologic findings of the removed lymph node showed caseating granuloma with macrophages. The clinical findings together with the laboratory evaluation and biopsy features were suggestive of mediastinal histoplasmosis as the cause of the dysphagia. Springer Japan, 2013 Dysphagia nationallicence Histoplasma nationallicence Mediastinal lymphadenopathy nationallicence Mediastinal histoplasmosis nationallicence Chaudhari Dhara Department of Internal Medicine, East Tennessee State University, 1008 Quality Circle, Apt 79, 37615, Johnson City, TN, USA aut Mckinney Jason Department of Gastroenterology, East Tennessee State University, Johnson City, TN, USA aut Hubbs Doris Department of Internal Medicine, East Tennessee State University, 1008 Quality Circle, Apt 79, 37615, Johnson City, TN, USA aut Young Mark Department of Gastroenterology, East Tennessee State University, Johnson City, TN, USA aut Clinical Journal of Gastroenterology Springer Japan 6/4(2013-08-01), 315-318 1865-7257 6:4<315 2013 6 12328 https://doi.org/10.1007/s12328-013-0405-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12328-013-0405-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chaudhari Dhara Department of Internal Medicine, East Tennessee State University, 1008 Quality Circle, Apt 79, 37615, Johnson City, TN, USA aut NATIONALLICENCE 700 1- Mckinney Jason Department of Gastroenterology, East Tennessee State University, Johnson City, TN, USA aut NATIONALLICENCE 700 1- Hubbs Doris Department of Internal Medicine, East Tennessee State University, 1008 Quality Circle, Apt 79, 37615, Johnson City, TN, USA aut NATIONALLICENCE 700 1- Young Mark Department of Gastroenterology, East Tennessee State University, Johnson City, TN, USA aut NATIONALLICENCE 773 0- Clinical Journal of Gastroenterology Springer Japan 6/4(2013-08-01), 315-318 1865-7257 6:4<315 2013 6 12328 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer