naa a22 4500 510816746 CHVBK 20180411083511.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s11468-012-9411-z doi (NATIONALLICENCE)springer-10.1007/s11468-012-9411-z Dual Polarization Measurements in the Hybrid Plasmonic Biosensors [Elektronische Daten] [F. Bahrami, M. Alam, J. Aitchison, M. Mojahedi] A novel affinity biosensor is proposed based on the hybrid plasmonic platform. The proposed biosensor benefits from the high sensitivity of the surface plasmon resonance (SPR), while at the same time, it is capable of performing measurements in both the TM and TE polarizations (p- and s-polarizations). Unlike the conventional SPR biosensors, the polarization diversity of the hybrid sensor allows for decoupling of the bulk index variations in the fluidic channels (due to variations in concentration, decomposition, temperature, and so on) from the surface properties of the attached molecules. Compatibility of the proposed hybrid plasmonic biosensor with standard Si-processing techniques and the simplicity of its design are other advantages of the sensor which makes its fabrication straightforward. The best figure of merit for the biosensor is defined based on the minimum detection limit and a genetic algorithm is used to optimize the device. A method of de-convolving the surface and bulk effects is also discussed. Springer Science+Business Media, LLC, 2012 Plasmonic nationallicence Polarization nationallicence Sensitivity nationallicence Limit of detection nationallicence Biosensor nationallicence Dielectric waveguide nationallicence Bahrami F. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut Alam M. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut Aitchison J. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut Mojahedi M. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut Plasmonics Springer US; http://www.springer-ny.com 8/2(2013-06-01), 465-473 1557-1955 8:2<465 2013 8 11468 https://doi.org/10.1007/s11468-012-9411-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11468-012-9411-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bahrami F. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut NATIONALLICENCE 700 1- Alam M. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut NATIONALLICENCE 700 1- Aitchison J. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut NATIONALLICENCE 700 1- Mojahedi M. Department of Electrical and Computer Engineering, University of Toronto, M5S 3 G4, Toronto, Ontario, Canada aut NATIONALLICENCE 773 0- Plasmonics Springer US; http://www.springer-ny.com 8/2(2013-06-01), 465-473 1557-1955 8:2<465 2013 8 11468 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer