naa a22 4500 510816770 CHVBK 20180411083511.0 cr unu---uuuuu 180411e20130601xx s 000 0 eng 10.1007/s11468-012-9376-y doi (NATIONALLICENCE)springer-10.1007/s11468-012-9376-y A Visualized Assay for Quercetin Based on the Formation of Silver-Gold Alloy Nanoparticles [Elektronische Daten] [Zhanguang Chen, Guoming Zhang, Xi Chen, Junhui Chen, Zhuoxian Fu] A visualized assay for quercetin (QU) was first developed based on the formation of silver-gold alloy nanoparticles in this contribution. With the ability to reduce metal ions to metal substances, QU could reduce Ag+ absorbed on the surface of gold nanoparticles to metallic silver. The thickness of the formed Ag shell and the color change of the solution were proportional to the concentration of QU. Therefore, visualized detection of QU could be realized by studying the surface resonance plasmon absorption spectra of the analytical systems after addition of different concentration of QU. Under optimum conditions, trace amount of QU could be detected in the linear range 9.0 × 10−7-1.0 × 10−4molL−1 with a detection limit of 6.5 × 10−7molL−1. The present assay was applied in the determination of QU in human serum and satisfactory results were obtained. This assay is simple, rapid, and cost-effective, and it is a powerful complement for the spectroscopy assays for QU. Also, it is the first visualized spectroscopic assay of QU until now. Springer Science+Business Media, LLC, 2012 Quercetin nationallicence Gold nanoparticles nationallicence Silver nanoparticles nationallicence Alloy nationallicence Visualized nationallicence Chen Zhanguang Department of Chemistry, Shantou University, 515063, Shantou, China aut Zhang Guoming Department of Chemistry, Shantou University, 515063, Shantou, China aut Chen Xi Guangdong Pharmaceutical University, 510006, Guangzhou, China aut Chen Junhui Department of Radiology, Peking University Shenzhen Hospital, 518036, Shenzhen, China aut Fu Zhuoxian Department of Chemistry, Shantou University, 515063, Shantou, China aut Plasmonics Springer US; http://www.springer-ny.com 8/2(2013-06-01), 201-207 1557-1955 8:2<201 2013 8 11468 https://doi.org/10.1007/s11468-012-9376-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11468-012-9376-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Zhanguang Department of Chemistry, Shantou University, 515063, Shantou, China aut NATIONALLICENCE 700 1- Zhang Guoming Department of Chemistry, Shantou University, 515063, Shantou, China aut NATIONALLICENCE 700 1- Chen Xi Guangdong Pharmaceutical University, 510006, Guangzhou, China aut NATIONALLICENCE 700 1- Chen Junhui Department of Radiology, Peking University Shenzhen Hospital, 518036, Shenzhen, China aut NATIONALLICENCE 700 1- Fu Zhuoxian Department of Chemistry, Shantou University, 515063, Shantou, China aut NATIONALLICENCE 773 0- Plasmonics Springer US; http://www.springer-ny.com 8/2(2013-06-01), 201-207 1557-1955 8:2<201 2013 8 11468 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer