naa a22 4500 51081848X CHVBK 20180411083519.0 cr unu---uuuuu 180411e20130801xx s 000 0 eng 10.1007/s12306-013-0277-9 doi (NATIONALLICENCE)springer-10.1007/s12306-013-0277-9 Atraumatic vertebral compression fractures: differential diagnosis between benign osteoporotic and malignant fractures by MRI [Elektronische Daten] [D. Cicala, F. Briganti, L. Casale, C. Rossi, L. Cagini, E. Cesarano, L. Brunese, M. Giganti] Atraumatic vertebral compression fractures are a common clinical problem, especially in elderly population. Metastases are the most frequent source of bone tumors, and the spine is a common site of metastatic disease; in case of cortical involvement or osteolysis, they may result in pathological compression fractures. Atraumatic compression fractures may result from other primary neoplasms of vertebrae and also from osteomyelitis, Paget's disease, hyperparathyroidism and other metabolic processes. Osteoporosis is a common source of vertebral compression fractures in elderly population, which may be indistinguishable from those of metastatic origin. The differentiation between osteoporotic compression fractures and malignant fracture is necessary to establish an appropriate staging and a therapeutic planning, especially in the acute and subacute stages. Anamnestic data about preexisting disease can be useful to individuate the potential cause of vertebral collapse. Plain radiography shows some difficulties in distinguishing whether the fracture represents a consequence of osteoporosis, a metastatic lesion or some other primary bone neoplasm. Computed tomography is one of the most suitable imaging techniques for the evaluation of bone structure and fragments and to establish the degree of cortical bone destruction; MR imaging (MRI) is the most helpful radiological investigation in order to provide the basis for the distinction between metastatic and acute osteoporotic compression fractures. The most relevant MRI findings to establish a differential diagnosis are described. Istituto Ortopedico Rizzoli, 2013 Vertebral fractures nationallicence Osteoporotic fractures nationallicence MRI nationallicence Cicala D. Department of Radiology, Villa Fiorita Clinic, Strada Statale Appia, Km 199,00, Località Camarelle, 81043, Capua, Caserta, Italy aut Briganti F. Department of Diagnostic Radiology and Radiotherapy, Federico II University of Naples, Naples, Italy aut Casale L. Department of Radiology, Sessa Aurunca Hospital, Caserta, Italy aut Rossi C. Second University of Naples, Department of Radiology, Naples, Italy aut Cagini L. Thoracic Surgery Unit, University of Perugia, Perugia, Italy aut Cesarano E. Radiology Section, Health Service, Navy Command of Brindisi, Brindisi, Italy aut Brunese L. Department of Health Science, Chair of Radiology, University of Molise, Campobasso, Italy aut Giganti M. Dipartimento di Scienze Chirurgiche, University of Ferrara, Ferrara, Italy aut MUSCULOSKELETAL SURGERY Springer Milan 97(2013-08-01), 169-179 2035-5106 97<169 2013 97 12306 https://doi.org/10.1007/s12306-013-0277-9 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s12306-013-0277-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cicala D. Department of Radiology, Villa Fiorita Clinic, Strada Statale Appia, Km 199,00, Località Camarelle, 81043, Capua, Caserta, Italy aut NATIONALLICENCE 700 1- Briganti F. Department of Diagnostic Radiology and Radiotherapy, Federico II University of Naples, Naples, Italy aut NATIONALLICENCE 700 1- Casale L. Department of Radiology, Sessa Aurunca Hospital, Caserta, Italy aut NATIONALLICENCE 700 1- Rossi C. Second University of Naples, Department of Radiology, Naples, Italy aut NATIONALLICENCE 700 1- Cagini L. Thoracic Surgery Unit, University of Perugia, Perugia, Italy aut NATIONALLICENCE 700 1- Cesarano E. Radiology Section, Health Service, Navy Command of Brindisi, Brindisi, Italy aut NATIONALLICENCE 700 1- Brunese L. Department of Health Science, Chair of Radiology, University of Molise, Campobasso, Italy aut NATIONALLICENCE 700 1- Giganti M. Dipartimento di Scienze Chirurgiche, University of Ferrara, Ferrara, Italy aut NATIONALLICENCE 773 0- MUSCULOSKELETAL SURGERY Springer Milan 97(2013-08-01), 169-179 2035-5106 97<169 2013 97 12306 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer