naa a22 4500 510819095 CHVBK 20180411083522.0 cr unu---uuuuu 180411e20130101xx s 000 0 eng 10.1007/s11814-012-0102-4 doi (NATIONALLICENCE)springer-10.1007/s11814-012-0102-4 Colorimetric detection of vesicle rupture by attack of Ag nanoparticles [Elektronische Daten] [Sohyang Shin, Younghun Kim] Generally, the cytotoxicity effects of nanomaterials on bio-organisms have been examined using live cells or mice by in-vivo or in-vitro testing. These methodologies, however, are time-consuming, and cell-membrane responses for cytotoxicity are often slow. Therefore, in this study, we proposed a simple testing method for colorimetric detection of dye-containing vesicles as biomimetic cell-membranes. When dye-containing vesicles are ruptured by attack of AgNPs (silver nanoparticles), dye in vesicles is released into the solution, and then the color of solution changes to that of dye. Because the ruptured vesicle causes an optical variation, we could easily and quickly monitor the vesicle rupture by AgNPs. And further, SPR (surface plasmon resonance spectroscopy) and TEM (transmission electron microscopy) analysis were carried out to confirm the vesicle rupturing. It will be provide indirect information for cytotoxicity of nanoparticles. Korean Institute of Chemical Engineers, Seoul, Korea, 2012 Dye-contained Vesicle nationallicence Silver Nanoparticle nationallicence Cytotoxicity Test nationallicence Shin Sohyang Department of Chemical Engineering, Kwangwoon University, 139-701, Seoul, Korea aut Kim Younghun Department of Chemical Engineering, Kwangwoon University, 139-701, Seoul, Korea aut Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/1(2013-01-01), 235-237 0256-1115 30:1<235 2013 30 11814 https://doi.org/10.1007/s11814-012-0102-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11814-012-0102-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shin Sohyang Department of Chemical Engineering, Kwangwoon University, 139-701, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Younghun Department of Chemical Engineering, Kwangwoon University, 139-701, Seoul, Korea aut NATIONALLICENCE 773 0- Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/1(2013-01-01), 235-237 0256-1115 30:1<235 2013 30 11814 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer