naa a22 4500 510819575 CHVBK 20180411083524.0 cr unu---uuuuu 180411e20130701xx s 000 0 eng 10.1007/s11814-013-0083-y doi (NATIONALLICENCE)springer-10.1007/s11814-013-0083-y Viruses as self-assembled nanocontainers for encapsulation of functional cargoes [Elektronische Daten] [Yuanzheng Wu, Hetong Yang, Hyun-Jae Shin] Viruses naturally exhibit an incredible variety of sophisticated nanostructures, which makes them ideal biological building blocks for nanoengineered material research. By mimicking their spontaneous assembly process, tremendous advances have been made towards utilizing virus and virus-like particles (VLPs) as protein cages, scaffolds, and templates for nanomaterials in the last few years. This review outlines recent progress in the field of bionanotechnology in which viruses are introduced to encapsulate various functional cargoes in a precise and controlled fashion. The encapsulation mechanisms are summarized into three main strategies: electrostatic interaction, chemical conjugation, and covalent attachment by genetic manipulation. The combination with chemical modification and genetic engineering heralds a brilliant future for fabrication of functional nanomaterials. These well-defined architectures will find attractive applications in biosensing, drug delivery, enzyme confinement, light-harvesting system, and pharmaceutical therapy. Korean Institute of Chemical Engineers, Seoul, Korea, 2013 Virus nationallicence Virus-like Particles (VLPs) nationallicence Encapsulation nationallicence Nanomaterials nationallicence Drug Delivery nationallicence Wu Yuanzheng Department of Chemical and Biochemical Engineering, Chosun University, #375, Seosuk-dong, Dong-gu, 501-759, Gwangju, Korea aut Yang Hetong Biotechnology Center of Shandong Academy of Sciences, No. 19 Keyuan Road, 250014, Jinan, China aut Shin Hyun-Jae Department of Chemical and Biochemical Engineering, Chosun University, #375, Seosuk-dong, Dong-gu, 501-759, Gwangju, Korea aut Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/7(2013-07-01), 1359-1367 0256-1115 30:7<1359 2013 30 11814 https://doi.org/10.1007/s11814-013-0083-y text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11814-013-0083-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wu Yuanzheng Department of Chemical and Biochemical Engineering, Chosun University, #375, Seosuk-dong, Dong-gu, 501-759, Gwangju, Korea aut NATIONALLICENCE 700 1- Yang Hetong Biotechnology Center of Shandong Academy of Sciences, No. 19 Keyuan Road, 250014, Jinan, China aut NATIONALLICENCE 700 1- Shin Hyun-Jae Department of Chemical and Biochemical Engineering, Chosun University, #375, Seosuk-dong, Dong-gu, 501-759, Gwangju, Korea aut NATIONALLICENCE 773 0- Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/7(2013-07-01), 1359-1367 0256-1115 30:7<1359 2013 30 11814 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer