naa a22 4500 510821103 CHVBK 20180411083532.0 cr unu---uuuuu 180411e20130501xx s 000 0 eng 10.1007/s11814-013-0012-0 doi (NATIONALLICENCE)springer-10.1007/s11814-013-0012-0 Application of Doehlert experimental design for the optimization of cadmium biosorption in an aqueous solution by marine yeast biomass of Yarrowia lipolytica [Elektronische Daten] [Sarat Imandi, Ramakrishna Chinthala, Silas Saka, Rama Vechalapu, Kiran Nalla] A cadmium biosorption process was optimized by varying three independent variables pH (4.5-7.5), initial cadmium ion concentration (10-30 mg L−1), and Yarrowia lipolytica dosage (3-5 g L−1) by using a Doehlert experimental design (DD) involving response surface methodology (RSM). For the maximum biosorption of cadmium ion in an aqueous solution by Y. lipolytica, a total of fifteen experimental runs were set and the experimental data fitted to the empirical second-order polynomial model of a suitable degree. The analysis of variance of the quadratic model demonstrates that the model was highly significant. Three-dimensional plots demonstrate relationships between the cadmium ion uptake with the paired variables (when other variable was kept at its optimal level), describing the behavior of biosorption system in a batch process. The model showed that cadmium uptake in aqueous solution was affected by all the three variables studied. The optimum values of the variables were found to be 6.43, 17.56 mg L−1 and 3.63 g L−1 for pH, initial cadmium ion concentration and biomass dosage, respectively, at a contact time of 40 min. At these optimal conditions, the maximum percentage biosorption of cadmium was predicted to be 48.89. The experimental values were in good agreement with predicted values and the correlation coefficient was found to be 0.9985. It showed that both monolayer adsorption and intra-particle diffusion mechanisms were effective in the cadmium biosorption process. Therefore, it is apparent that the DD involving RSM not only gives valuable information on interactions between the variables but also leads to identification of feasible optimum values of the studied variables. Korean Institute of Chemical Engineers, Seoul, Korea, 2013 Biosorption nationallicence Doehlert Experimental Design nationallicence Response Surface Methodology nationallicence Yarrowia lipolytica nationallicence Imandi Sarat Department of Biotechnology, GITAM Institute of Technology, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut Chinthala Ramakrishna Department of Environmental studies, GITAM Institute of Sciences, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut Saka Silas Department of Biotechnology, GITAM Institute of Technology, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut Vechalapu Rama Department of Biotechnology, GITAM Institute of Technology, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut Nalla Kiran UGC Affairs & Research Activities, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/5(2013-05-01), 1067-1075 0256-1115 30:5<1067 2013 30 11814 https://doi.org/10.1007/s11814-013-0012-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11814-013-0012-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Imandi Sarat Department of Biotechnology, GITAM Institute of Technology, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut NATIONALLICENCE 700 1- Chinthala Ramakrishna Department of Environmental studies, GITAM Institute of Sciences, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut NATIONALLICENCE 700 1- Saka Silas Department of Biotechnology, GITAM Institute of Technology, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut NATIONALLICENCE 700 1- Vechalapu Rama Department of Biotechnology, GITAM Institute of Technology, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut NATIONALLICENCE 700 1- Nalla Kiran UGC Affairs & Research Activities, GITAM University, 530 045, Gandhinagar, Rushikonda, Visakhapatnam, AP, India aut NATIONALLICENCE 773 0- Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/5(2013-05-01), 1067-1075 0256-1115 30:5<1067 2013 30 11814 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer