naa a22 4500 510821383 CHVBK 20180411083534.0 cr unu---uuuuu 180411e20130201xx s 000 0 eng 10.1007/s11814-012-0155-4 doi (NATIONALLICENCE)springer-10.1007/s11814-012-0155-4 Effect of agglomeration of silver nanoparticle on nanotoxicity depression [Elektronische Daten] [Eunjoo Bae, Byung-Cheun Lee, Younghun Kim, Kyunghee Choi, Jongheop Yi] Silver nanoparticles (AgNPs) are used commercially in a variety of applications, including textiles, cosmetics, spray cleaning agents, and metal products. AgNP itself, however, is classified as an environmental hazard by Environmental Protection Agency (EPA, USA) Nanotechnology White Paper, due to its toxic, persistent and bioaccumulative characteristics when exposed to the environment. We investigated the cumulative mortality and abnormalities in Japanese medaka (Oryziaslatipes) embryos after exposure to AgNPs. Free AgNPs in solution have a high activity with respect to biological interactions regarding blocking blood flow and distribution of AgNPs into the cells from head to tail of hatched O. latipes. Interestingly, the agglomeration of AgNPs (loss of nanosized characteristics) played an important role in the environmental toxicity. The present study demonstrated that when the AgNPs were exposed in the ecosystem and then formed agglomerates, nanotoxicity was reduced. Korean Institute of Chemical Engineers, Seoul, Korea, 2012 Nanomaterials nationallicence Silver Nanoparticles nationallicence Nano-hazard nationallicence Bioaccumulation nationallicence Agglomeration nationallicence Bae Eunjoo School of Chemical and Biological Engineering, Seoul National University, 151-742, Seoul, Korea aut Lee Byung-Cheun National Institute of Environmental Research, 404-708, Incheon, Korea aut Kim Younghun Department of Chemical Engineering, Kwangwoon University, 139-701, Seoul, Korea aut Choi Kyunghee National Institute of Environmental Research, 404-708, Incheon, Korea aut Yi Jongheop School of Chemical and Biological Engineering, Seoul National University, 151-742, Seoul, Korea aut Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/2(2013-02-01), 364-368 0256-1115 30:2<364 2013 30 11814 https://doi.org/10.1007/s11814-012-0155-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11814-012-0155-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bae Eunjoo School of Chemical and Biological Engineering, Seoul National University, 151-742, Seoul, Korea aut NATIONALLICENCE 700 1- Lee Byung-Cheun National Institute of Environmental Research, 404-708, Incheon, Korea aut NATIONALLICENCE 700 1- Kim Younghun Department of Chemical Engineering, Kwangwoon University, 139-701, Seoul, Korea aut NATIONALLICENCE 700 1- Choi Kyunghee National Institute of Environmental Research, 404-708, Incheon, Korea aut NATIONALLICENCE 700 1- Yi Jongheop School of Chemical and Biological Engineering, Seoul National University, 151-742, Seoul, Korea aut NATIONALLICENCE 773 0- Korean Journal of Chemical Engineering Springer US; http://www.springer-ny.com 30/2(2013-02-01), 364-368 0256-1115 30:2<364 2013 30 11814 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer