The Swiss approach to precision medicine
| LEADER | naa a22 4500 | ||
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| 001 | 52878191X | ||
| 005 | 20180924065512.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 180924e20180102xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.3929/ethz-b-000274911 |2 doi |
| 035 | |a (ETHRESEARCH)oai:www.research-collecti.ethz.ch:20.500.11850/274911 | ||
| 245 | 0 | 4 | |a The Swiss approach to precision medicine |h [Elektronische Daten] |c [Peter J. Meier-Abt, Adrien K. Lawrence, Liselotte Selter, Effy Vayena, Torsten Schwede] |
| 246 | 0 | |a Swiss Med Wkly | |
| 506 | |a Open access |2 ethresearch | ||
| 520 | 3 | |a Precision or personalised medicine/health aims to prevent, diagnose and treat diseases by taking into account individual variability of genes, environment and lifestyle for each person. In order to tap the full potential of the increasing amount of molecular, biological and clinical health data, new infrastructures are required that permit collection, storage and analysis of high quality data and adequately link biobank samples to clinical data. Many countries have started to build interconnected "precision/personalised medicine ecosystems”, but the federalist and heterogeneous healthcare system has so far prevented nationwide coordinated activities in Switzerland. Therefore, the Swiss Personalized Health Network (SPHN) initiative has been launched. Its mission is to lay the foundations for personalised health on a national level by the development of a nationally coordinated interoperable data infrastructure to enable nationwide accessibility and exchange of health-related data. This paper describes the goals of SPHN, its current procedures and funding regulations, its organisation, its ethical and legal framework for responsible data processing, its data management infrastructure and information security and its relevant partnerships with other organisations and institutions. Although the SPHN initiative starts with the institutions of higher education such as university hospitals, universities and the ETH domain, other hospitals, public health institutions and medical practitioners, as well as private institutions such as industry and health insurers, will be included into the initiative at a later time point. Ultimately, the SPHN initiative shall lead to the development of an effective Swiss personalised health ecosystem, which is required to advance effective individual prevention, diagnosis and treatment of disease states and to push Switzerland to the international forefront of personalised health-related research and health care. | |
| 540 | |a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International |u http://creativecommons.org/licenses/by-nc-nd/4.0 |2 ethresearch | ||
| 690 | 7 | |a Precision medicine |2 ethresearch | |
| 690 | 7 | |a personalised health |2 ethresearch | |
| 690 | 7 | |a Swiss Personalized Health Network (SPHN) initiative |2 ethresearch | |
| 690 | 7 | |a Swiss interoperable health data infrastructure |2 ethresearch | |
| 690 | 7 | |a ethical and legal framework for responsible health data processing |2 ethresearch | |
| 690 | 7 | |a health data management infrastructure and information security |2 ethresearch | |
| 700 | 1 | |a Meier-Abt |D Peter J. |e joint author | |
| 700 | 1 | |a Lawrence |D Adrien K. |e joint author | |
| 700 | 1 | |a Selter |D Liselotte |e joint author | |
| 700 | 1 | |a Vayena |D Effy |e joint author | |
| 700 | 1 | |a Schwede |D Torsten |e joint author | |
| 773 | 0 | |t Swiss Medical Weekly |d Basel : EMH Schweizerischer Ärzteverlag |x 1424-7860 | |
| 856 | 4 | 0 | |u http://hdl.handle.net/20.500.11850/274911 |q text/html |z WWW-Backlink auf das Repository (Open access) |
| 908 | |D 1 |a Journal Article |2 ethresearch | ||
| 950 | |B ETHRESEARCH |P 856 |E 40 |u http://hdl.handle.net/20.500.11850/274911 |q text/html |z WWW-Backlink auf das Repository (Open access) | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Meier-Abt |D Peter J. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Lawrence |D Adrien K. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Selter |D Liselotte |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Vayena |D Effy |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Schwede |D Torsten |e joint author | ||
| 950 | |B ETHRESEARCH |P 773 |E 0- |t Swiss Medical Weekly |d Basel : EMH Schweizerischer Ärzteverlag |x 1424-7860 | ||
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B ETHRESEARCH |F ETHRESEARCH |b ETHRESEARCH |j Journal Article |c Open access | ||