Is Motor Learning Mediated by tDCS Intensity?

Verfasser / Beitragende:
[Koen Cuypers, Daphnie J.F. Leenus, Femke E. van den Berg, Michael A. Nitsche, Herbert Thijs, Nicole Wenderoth, Raf L.J. Meesen]
Ort, Verlag, Jahr:
2013
Enthalten in:
PLoS ONE, 8 (6), p. e67344
Format:
Artikel (online)
ID: 528782517
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024 7 0 |a 10.3929/ethz-b-000070752  |2 doi 
024 7 0 |a 10.1371/journal.pone.0067344  |2 doi 
035 |a (ETHRESEARCH)oai:www.research-collecti.ethz.ch:20.500.11850/70752 
245 0 0 |a Is Motor Learning Mediated by tDCS Intensity?  |h [Elektronische Daten]  |c [Koen Cuypers, Daphnie J.F. Leenus, Femke E. van den Berg, Michael A. Nitsche, Herbert Thijs, Nicole Wenderoth, Raf L.J. Meesen] 
246 0 |a PLoS ONE 
506 |a Open access  |2 ethresearch 
520 3 |a Although tDCS has been shown to improve motor learning, previous studies reported rather small effects. Since physiological effects of tDCS depend on intensity, the present study evaluated this parameter in order to enhance the effect of tDCS on skill acquisition. The effect of different stimulation intensities of anodal tDCS (atDCS) was investigated in a double blind, sham controlled crossover design. In each condition, thirteen healthy subjects were instructed to perform a unimanual motor (sequence) learning task. Our results showed (1) a significant increase in the slope of the learning curve and (2) a significant improvement in motor performance at retention for 1.5 mA atDCS as compared to sham tDCS. No significant differences were reported between 1 mA atDCS and sham tDCS; and between 1.5 mA atDCS and 1 mA atDCS. 
540 |a Creative Commons Attribution 3.0 Unported  |u http://creativecommons.org/licenses/by/3.0  |2 ethresearch 
700 1 |a Cuypers  |D Koen  |e joint author 
700 1 |a Leenus  |D Daphnie J.F.  |e joint author 
700 1 |a van den Berg  |D Femke E.  |e joint author 
700 1 |a Nitsche  |D Michael A.  |e joint author 
700 1 |a Thijs  |D Herbert  |e joint author 
700 1 |a Wenderoth  |D Nicole  |e joint author 
700 1 |a Meesen  |D Raf L.J.  |e joint author 
773 0 |t PLoS ONE  |d San Francisco, CA, USA : Public Library of Science  |g 8 (6), p. e67344  |x 1932-6203 
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950 |B ETHRESEARCH  |P 700  |E 1-  |a Cuypers  |D Koen  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Leenus  |D Daphnie J.F.  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a van den Berg  |D Femke E.  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Nitsche  |D Michael A.  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Thijs  |D Herbert  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Wenderoth  |D Nicole  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Meesen  |D Raf L.J.  |e joint author 
950 |B ETHRESEARCH  |P 773  |E 0-  |t PLoS ONE  |d San Francisco, CA, USA : Public Library of Science  |g 8 (6), p. e67344  |x 1932-6203 
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