The contrasting phylodynamics of human influenza B viruses
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 528785508 | ||
| 005 | 20190908091347.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 180924e201501 xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.3929/ethz-b-000098273 |2 doi |
| 024 | 7 | 0 | |a 10.7554/eLife.05055 |2 doi |
| 035 | |a (ETHRESEARCH)oai:www.research-collecti.ethz.ch:20.500.11850/98273 | ||
| 245 | 0 | 4 | |a The contrasting phylodynamics of human influenza B viruses |h [Elektronische Daten] |c [Dhanasekaran Vijaykrishna, Edward C. Holmes, Udayan Joseph, Mathieu Fourment, Yvonne C.F. Su, Rebecca A. Halpin, Raphael T.C. Lee, Yi-Mo Deng, Vithiagaran Gunalan, Xudong Lin, Timothy B. Stockwell, Nadia B. Fedorova, Bin Zhou, Natalie Spirason, Denise Kühnert, Veronika Boskova, Tanja; id_orcid 0000-0001-6431-535X Stadler, Anna-Maria Costa, Dominic E. Dwyer, Q. Sue Huang, Lance C. Jennings, William Rawlinson, Sheena G. Sullivan, Aeron C. Hurt, Sebastian Maurer-Stroh, David E. Wentworth, Gavin J.D. Smith, Ian G. Barr] |
| 506 | |a Open access |2 ethresearch | ||
| 520 | 3 | |a A complex interplay of viral, host, and ecological factors shapes the spatio-temporal incidence and evolution of human influenza viruses. Although considerable attention has been paid to influenza A viruses, a lack of equivalent data means that an integrated evolutionary and epidemiological framework has until now not been available for influenza B viruses, despite their significant disease burden. Through the analysis of over 900 full genomes from an epidemiological collection of more than 26,000 strains from Australia and New Zealand, we reveal fundamental differences in the phylodynamics of the two co-circulating lineages of influenza B virus (Victoria and Yamagata), showing that their individual dynamics are determined by a complex relationship between virus transmission, age of infection, and receptor binding preference. In sum, this work identifies new factors that are important determinants of influenza B evolution and epidemiology. | |
| 540 | |a Creative Commons Attribution 4.0 International |u http://creativecommons.org/licenses/by/4.0 |2 ethresearch | ||
| 700 | 1 | |a Vijaykrishna |D Dhanasekaran |e joint author | |
| 700 | 1 | |a Holmes |D Edward C. |e joint author | |
| 700 | 1 | |a Joseph |D Udayan |e joint author | |
| 700 | 1 | |a Fourment |D Mathieu |e joint author | |
| 700 | 1 | |a Su |D Yvonne C.F. |e joint author | |
| 700 | 1 | |a Halpin |D Rebecca A. |e joint author | |
| 700 | 1 | |a Lee |D Raphael T.C. |e joint author | |
| 700 | 1 | |a Deng |D Yi-Mo |e joint author | |
| 700 | 1 | |a Gunalan |D Vithiagaran |e joint author | |
| 700 | 1 | |a Lin |D Xudong |e joint author | |
| 700 | 1 | |a Stockwell |D Timothy B. |e joint author | |
| 700 | 1 | |a Fedorova |D Nadia B. |e joint author | |
| 700 | 1 | |a Zhou |D Bin |e joint author | |
| 700 | 1 | |a Spirason |D Natalie |e joint author | |
| 700 | 1 | |a Kühnert |D Denise |e joint author | |
| 700 | 1 | |a Boskova |D Veronika |e joint author | |
| 700 | 1 | |a Stadler |D Tanja; id_orcid 0000-0001-6431-535X |e joint author | |
| 700 | 1 | |a Costa |D Anna-Maria |e joint author | |
| 700 | 1 | |a Dwyer |D Dominic E. |e joint author | |
| 700 | 1 | |a Huang |D Q. Sue |e joint author | |
| 700 | 1 | |a Jennings |D Lance C. |e joint author | |
| 700 | 1 | |a Rawlinson |D William |e joint author | |
| 700 | 1 | |a Sullivan |D Sheena G. |e joint author | |
| 700 | 1 | |a Hurt |D Aeron C. |e joint author | |
| 700 | 1 | |a Maurer-Stroh |D Sebastian |e joint author | |
| 700 | 1 | |a Wentworth |D David E. |e joint author | |
| 700 | 1 | |a Smith |D Gavin J.D. |e joint author | |
| 700 | 1 | |a Barr |D Ian G. |e joint author | |
| 773 | 0 | |t eLife |d Cambridge : eLife Sciences Publications |g 4, p. e05055 |x 2050-084X | |
| 856 | 4 | 0 | |u http://hdl.handle.net/20.500.11850/98273 |q text/html |z WWW-Backlink auf das Repository (Open access) |
| 908 | |D 1 |a Journal Article |2 ethresearch | ||
| 950 | |B ETHRESEARCH |P 856 |E 40 |u http://hdl.handle.net/20.500.11850/98273 |q text/html |z WWW-Backlink auf das Repository (Open access) | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Vijaykrishna |D Dhanasekaran |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Holmes |D Edward C. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Joseph |D Udayan |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Fourment |D Mathieu |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Su |D Yvonne C.F. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Halpin |D Rebecca A. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Lee |D Raphael T.C. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Deng |D Yi-Mo |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Gunalan |D Vithiagaran |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Lin |D Xudong |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Stockwell |D Timothy B. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Fedorova |D Nadia B. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Zhou |D Bin |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Spirason |D Natalie |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Kühnert |D Denise |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Boskova |D Veronika |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Stadler |D Tanja; id_orcid 0000-0001-6431-535X |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Costa |D Anna-Maria |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Dwyer |D Dominic E. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Huang |D Q. Sue |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Jennings |D Lance C. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Rawlinson |D William |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Sullivan |D Sheena G. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Hurt |D Aeron C. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Maurer-Stroh |D Sebastian |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Wentworth |D David E. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Smith |D Gavin J.D. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Barr |D Ian G. |e joint author | ||
| 950 | |B ETHRESEARCH |P 773 |E 0- |t eLife |d Cambridge : eLife Sciences Publications |g 4, p. e05055 |x 2050-084X | ||
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B ETHRESEARCH |F ETHRESEARCH |b ETHRESEARCH |j Journal Article |c Open access | ||