An open-source computational and data resource to analyze digital maps of immunopeptidomes
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 528785583 | ||
| 005 | 20190908091347.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 180924e201507 xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.3929/ethz-b-000107549 |2 doi |
| 024 | 7 | 0 | |a 10.7554/eLife.07661 |2 doi |
| 035 | |a (ETHRESEARCH)oai:www.research-collecti.ethz.ch:20.500.11850/107549 | ||
| 245 | 0 | 3 | |a An open-source computational and data resource to analyze digital maps of immunopeptidomes |h [Elektronische Daten] |c [Etienne Caron, Lucia Espona, Daniel J. Kowalewski, Heiko Schuster, Nicola Ternette, Adán Alpízar, Ralf B. Schittenhelm, Sri H. Ramarathinam, Cecilia S. Lindestam Arlehamn, Ching Chiek Koh, Ludovic; id_orcid 0000-0002-1001-3265 Gillet, Armin Rabsteyn, Pedro Navarro, Sangtae Kim, Henry Lam, Theo Sturm, Miguel Marcilla, Alessandro Sette, David S. Campbell, Eric W. Deutsch, Robert L. Moritz, Anthony W. Purcell, Hans-Georg Rammensee, Stefan Stevanović, Ruedi Aebersold] |
| 506 | |a Open access |2 ethresearch | ||
| 520 | 3 | |a We present a novel mass spectrometry-based high-throughput workflow and an open-source computational and data resource to reproducibly identify and quantify HLA-associated peptides. Collectively, the resources support the generation of HLA allele-specific peptide assay libraries consisting of consensus fragment ion spectra, and the analysis of quantitative digital maps of HLA peptidomes generated from a range of biological sources by SWATH mass spectrometry (MS). This study represents the first community-based effort to develop a robust platform for the reproducible and quantitative measurement of the entire repertoire of peptides presented by HLA molecules, an essential step towards the design of efficient immunotherapies. | |
| 540 | |a Creative Commons Attribution 4.0 International |u http://creativecommons.org/licenses/by/4.0 |2 ethresearch | ||
| 700 | 1 | |a Caron |D Etienne |e joint author | |
| 700 | 1 | |a Espona |D Lucia |e joint author | |
| 700 | 1 | |a Kowalewski |D Daniel J. |e joint author | |
| 700 | 1 | |a Schuster |D Heiko |e joint author | |
| 700 | 1 | |a Ternette |D Nicola |e joint author | |
| 700 | 1 | |a Alpízar |D Adán |e joint author | |
| 700 | 1 | |a Schittenhelm |D Ralf B. |e joint author | |
| 700 | 1 | |a Ramarathinam |D Sri H. |e joint author | |
| 700 | 1 | |a Lindestam Arlehamn |D Cecilia S. |e joint author | |
| 700 | 1 | |a Koh |D Ching Chiek |e joint author | |
| 700 | 1 | |a Gillet |D Ludovic; id_orcid 0000-0002-1001-3265 |e joint author | |
| 700 | 1 | |a Rabsteyn |D Armin |e joint author | |
| 700 | 1 | |a Navarro |D Pedro |e joint author | |
| 700 | 1 | |a Kim |D Sangtae |e joint author | |
| 700 | 1 | |a Lam |D Henry |e joint author | |
| 700 | 1 | |a Sturm |D Theo |e joint author | |
| 700 | 1 | |a Marcilla |D Miguel |e joint author | |
| 700 | 1 | |a Sette |D Alessandro |e joint author | |
| 700 | 1 | |a Campbell |D David S. |e joint author | |
| 700 | 1 | |a Deutsch |D Eric W. |e joint author | |
| 700 | 1 | |a Moritz |D Robert L. |e joint author | |
| 700 | 1 | |a Purcell |D Anthony W. |e joint author | |
| 700 | 1 | |a Rammensee |D Hans-Georg |e joint author | |
| 700 | 1 | |a Stevanović |D Stefan |e joint author | |
| 700 | 1 | |a Aebersold |D Ruedi |e joint author | |
| 773 | 0 | |t eLife |d Cambridge : eLife Sciences Publications |g 4, p. e07661 |x 2050-084X | |
| 856 | 4 | 0 | |u http://hdl.handle.net/20.500.11850/107549 |q text/html |z WWW-Backlink auf das Repository (Open access) |
| 908 | |D 1 |a Journal Article |2 ethresearch | ||
| 950 | |B ETHRESEARCH |P 856 |E 40 |u http://hdl.handle.net/20.500.11850/107549 |q text/html |z WWW-Backlink auf das Repository (Open access) | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Caron |D Etienne |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Espona |D Lucia |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Kowalewski |D Daniel J. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Schuster |D Heiko |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Ternette |D Nicola |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Alpízar |D Adán |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Schittenhelm |D Ralf B. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Ramarathinam |D Sri H. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Lindestam Arlehamn |D Cecilia S. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Koh |D Ching Chiek |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Gillet |D Ludovic; id_orcid 0000-0002-1001-3265 |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Rabsteyn |D Armin |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Navarro |D Pedro |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Kim |D Sangtae |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Lam |D Henry |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Sturm |D Theo |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Marcilla |D Miguel |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Sette |D Alessandro |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Campbell |D David S. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Deutsch |D Eric W. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Moritz |D Robert L. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Purcell |D Anthony W. |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Rammensee |D Hans-Georg |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Stevanović |D Stefan |e joint author | ||
| 950 | |B ETHRESEARCH |P 700 |E 1- |a Aebersold |D Ruedi |e joint author | ||
| 950 | |B ETHRESEARCH |P 773 |E 0- |t eLife |d Cambridge : eLife Sciences Publications |g 4, p. e07661 |x 2050-084X | ||
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 949 | |B ETHRESEARCH |F ETHRESEARCH |b ETHRESEARCH |j Journal Article |c Open access | ||