Boundaries steer the contraction of active gels

Verfasser / Beitragende:
[Matthias Schuppler, Felix C. Keber, Felix C. Kröger, Andreas R. Bausch]
Ort, Verlag, Jahr:
2016
Enthalten in:
Nature Communications, 7, p. 13120
Format:
Artikel (online)
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024 7 0 |a 10.3929/ethz-b-000122114  |2 doi 
024 7 0 |a 10.1038/ncomms13120  |2 doi 
035 |a (ETHRESEARCH)oai:www.research-collecti.ethz.ch:20.500.11850/122114 
245 0 0 |a Boundaries steer the contraction of active gels  |h [Elektronische Daten]  |c [Matthias Schuppler, Felix C. Keber, Felix C. Kröger, Andreas R. Bausch] 
246 0 |a Nat Commun 
506 |a Open access  |2 ethresearch 
520 3 |a Cells set up contractile actin arrays to drive various shape changes and to exert forces to their environment. To understand their assembly process, we present here a reconstituted contractile system, comprising F-actin and myosin II filaments, where we can control the local activation of myosin by light. By stimulating different symmetries, we show that the force balancing at the boundaries determine the shape changes as well as the dynamics of the global contraction. Spatially anisotropic attachment of initially isotropic networks leads to a self-organization of highly aligned contractile fibres, being reminiscent of the order formation in muscles or stress fibres. The observed shape changes and dynamics are fully recovered by a minimal physical model. 
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700 1 |a Schuppler  |D Matthias  |e joint author 
700 1 |a Keber  |D Felix C.  |e joint author 
700 1 |a Kröger  |D Felix C.  |e joint author 
700 1 |a Bausch  |D Andreas R.  |e joint author 
773 0 |t Nature Communications  |d London : Nature Publishing Group  |g 7, p. 13120  |x 2041-1723 
856 4 0 |u http://hdl.handle.net/20.500.11850/122114  |q text/html  |z WWW-Backlink auf das Repository (Open access) 
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950 |B ETHRESEARCH  |P 856  |E 40  |u http://hdl.handle.net/20.500.11850/122114  |q text/html  |z WWW-Backlink auf das Repository (Open access) 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Schuppler  |D Matthias  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Keber  |D Felix C.  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Kröger  |D Felix C.  |e joint author 
950 |B ETHRESEARCH  |P 700  |E 1-  |a Bausch  |D Andreas R.  |e joint author 
950 |B ETHRESEARCH  |P 773  |E 0-  |t Nature Communications  |d London : Nature Publishing Group  |g 7, p. 13120  |x 2041-1723 
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949 |B ETHRESEARCH  |F ETHRESEARCH  |b ETHRESEARCH  |j Journal Article  |c Open access