caa a22 4500 528788051 CHVBK 20190720032000.0 cr unu---uuuuu 180924e201808 xx s 000 0 eng 10.1038/s41477-018-0213-y doi (SERVAL)BIB_98E3F015A332 30061749 pmid 000443861300015 isiid Minimum requirements for changing and maintaining endodermis cell identity in the Arabidopsis root [Elektronische Daten] [C. Drapek, E.E. Sparks, P. Marhavy, I. Taylor, T.G. Andersen, J.H. Hennacy, N. Geldner, P.N. Benfey] Changes in gene regulation during differentiation are governed by networks of transcription factors. The Arabidopsis root endodermis is a tractable model to address how transcription factors contribute to differentiation. We used a bottom-up approach to understand the extent to which transcription factors that are required for endodermis differentiation can confer endodermis identity to a non-native cell type. Our results show that the transcription factors SHORTROOT and MYB36 alone have limited ability to induce ectopic endodermal features in the absence of additional cues. The stele-derived signalling peptide CIF2 stabilizes SHORTROOT-induced endodermis identity acquisition. The outcome is a partially impermeable barrier deposited in the subepidermal cell layer, which has a transcriptional signature similar to the endodermis. These results demonstrate that other root cell types can be forced to differentiate into the endodermis and highlight a previously unappreciated role for receptor kinase signalling in maintaining endodermis identity. Drapek C. aut Sparks E.E. aut Marhavy P. aut Taylor I. aut Andersen T.G. aut Hennacy J.H. aut Geldner N. aut Benfey P.N. aut Nature plants 4/8(2018-08), 586-595 4:8<586-595 2018 4 1 article serval SERVAL 700 1- Drapek C. aut SERVAL 700 1- Sparks E.E. aut SERVAL 700 1- Marhavy P. aut SERVAL 700 1- Taylor I. aut SERVAL 700 1- Andersen T.G. aut SERVAL 700 1- Hennacy J.H. aut SERVAL 700 1- Geldner N. aut SERVAL 700 1- Benfey P.N. aut SERVAL 773 0- Nature plants 4/8(2018-08), 586-595 4:8<586-595 2018 4 BK010053 XK010053 XK010000 SERVAL SERVAL SERVAL article