Clinical immunology

principles and practice

Verfasser / Beitragende:
edited by Robert Rich, MD [and five others]
Ort, Verlag, Jahr:
[Amsterdam] : Elsevier, 2019
Beschreibung:
1 online resource (xviii, 1373 pages) : illustrations (chiefly color)
Format:
Buch (online)
Ausgabe:
Fifth edition.
Online Zugang:
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020 |a 978-0-7020-6896-6 
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130 0 |a Clinical immunology (Rich) 
245 1 0 |a Clinical immunology  |b principles and practice  |c edited by Robert Rich, MD [and five others] 
250 |a Fifth edition. 
264 1 |a [Amsterdam]  |b Elsevier  |c 2019 
264 4 |c ©2019 
300 |a 1 online resource (xviii, 1373 pages)  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent/eng 
337 |a computer  |b c  |2 rdamedia/eng 
338 |a online resource  |b cr  |2 rdacarrier/eng 
504 |a Includes bibliographical references and index. 
505 0 |a Section 1: Principles of immune response. The human immune response -- Organization of the immune system -- Innate immunity -- Antigen receptor genes, gene products, and co-receptors -- The major histocompatibility complex -- Antigens and antigen presentation -- B-cell development and differentiation -- T-cell development -- Cytokines and cytokine receptors -- Chemokines and chemokine receptors -- Lymphocyte adhesion and trafficking -- T-cell activation and tolerance -- Regulated cell death -- The microbiota in immunity and inflammation -- Section 2: Host defense mechanisms and inflammation. Immunoglobulin function -- Helper T-cell subsets and control of the inflammatory response -- Cytotoxic T lymphocytes and natural killer cells -- Regulatory immune cells -- Host defenses in the skin -- Host defenses at mucosal surfaces -- Complement in host deficiencies and diseases -- Phagocyte deficiencies -- Mast cells, basophils, and mastocytosis -- Eosinophils and eosinophilia -- Section 3: Host defenses to infectious agents. Host defenses to viruses -- Host defenses to intracellular bacteria -- Host defenses to extracellular bacteria -- Host defenses to spirochetes -- Host defenses to fungi -- Host defenses to protozoa -- Host defenses to helminths -- Section 4: Immunologic deficiencies. Approach to the evaluation of the immunodeficient patient -- Human genomics in immunology -- Primary antibody deficiencies -- Primary T-cell immunodeficiencies -- Immunodeficiencies at the interface of innate and adaptive immunity -- Infections in the immunocompromised host -- Immune deficiencies at the extremes of age -- HIV infection and acquired immunodeficiency syndrome -- Autoantibody mediated phenocopies of primary immunodeficiency diseases -- Section 5: Allergic diseases. Immunological mechanisms of airway diseases and pathways to therapy -- Urticaria, angioedema, and anaphylaxis -- Allergic reactions to stinging and biting insects -- Atopic and contact dermatitis -- Food allergy -- Eosinophil-associated gastrointestinal disorders -- Allergic disorders of the eye -- Drug hypersensitivity -- Occupational respiratory allergies -- 
505 0 |a Section 6: Systemic immune diseases. Mechanisms of autoimmunity -- Systemic lupus erythematosus -- Rheumatoid arthritis -- Juvenile idiopathic arthritis -- Sjögren's syndrome -- Scleroderma-systemic sclerosis -- Inflammatory muscle diseases -- Spondyloarthritis -- Small and medium vessel primary vasculitis -- Large-vessel vasculitides -- Systemic autoinflammatory syndromes -- Antiphospholipid syndrome -- Section 7: Organ-specific inflammatory disease. Immunohematologic disorders -- Bullous diseases of the skin and mucous membranes -- Immunology of psoriasis -- Myasthenia gravis -- Multiple sclerosis -- Autoimmune peripheral neuropathies -- Immunologic renal diseases -- Inflammation and atherothrombosis -- Autoimmune thyroid diseases -- Diabetes and related autoimmune diseases -- Immunologic lung diseases -- Sarcoidosis -- Immunologic ocular disease -- Immunologic diseases of the gastrointestinal tract -- Inflammatory hepatobiliary diseases -- Section 8: Immunology of neoplasia. Tumor immunotherapy -- Lymphoid leukemias -- Lymphomas -- Monoclonal gammopathies -- Section 9: Transplantation. Concepts and challenges in organ transplantation: rejection, immunosuppression, and tolerance -- Immune reconstitution therapy for immunodeficiency -- Hematopoietic stem cell transplantation for malignant diseases -- Section 10: Prevention and therapy of immunologic diseases. Immunoglobulin therapy: replacement and immunomodulation -- Gene therapy -- Glucocorticoids -- Immunomodulating pharmaceuticals -- Protein kinase antagonists as therapeutic agents for immunological and inflammatory disorders -- Biological modifiers of inflammation -- Vaccines -- Immunotherapy of allergic disease -- Section 11: Diagnostic immunology. Flow cytometry -- Assessment of functional immune responses -- Assessment of neutrophil function -- Assessment of human allergic diseases -- Molecular methods -- Appendices. Selected CD molecules and their characteristics -- Laboratory reference values -- Vaccine schedules. 
506 |a Lizenzbedingungen können den Zugang einschränken. License restrictions may limit access. 
650 1 2 |a Immune System  |x physiology  |0 https://id.nlm.nih.gov/mesh/D007107Q000502 
650 2 2 |a Immune System Diseases  |x immunology  |0 https://id.nlm.nih.gov/mesh/D007154Q000276 
650 2 2 |a Immunity  |x physiology  |0 https://id.nlm.nih.gov/mesh/D007109Q000502 
700 1 |a Rich  |D Robert R.  |e editor 
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