naa a22 4500 530185563 CHVBK 20181026074446.0 cr unu---uuuuu 181026e201811 xx s 000 0 eng 10.1016/j.resuscitation.2018.08.023 doi (SERVAL)BIB_EDE401C6FD4D 30153468 pmid 000446854900012 isiid Does continuous EEG influence prognosis in patients after cardiac arrest? [Elektronische Daten] [D. Fatuzzo, I. Beuchat, V. Alvarez, J. Novy, M. Oddo, A.O. Rossetti] Electroencephalography (EEG) is a key modality for assessment of prognosis following cardiac arrest (CA); however, whether continuous EEG (cEEG) is superior to routine intermittent EEG (rEEG) remains debated. We examined the impact of cEEG (&gt;18 h) vs. rEEG (&lt;30 min) on outcome in comatose CA patients as part of multimodal prognostication. We analysed a large prospective registry of comatose post-CA adults (n = 497; 2009-2018), stratified based on whether they received cEEG (n = 62) or rEEG (n = 435), including standardized reactivity testing at two time-points. The primary endpoint was the impact of cEEG vs. rEEG on Glasgow-Pittsburgh Cerebral Performance Categories (CPC) at three months; we also assessed impact on time to death. Main patients' baseline clinical characteristics and CPC scores were comparable between the EEG groups. By multivariable analysis age, non-shockable rhythm, presence of early myoclonus, absent EEG background reactivity, absent somato-sensory evoked potentials, and serum NSE were independently associated with poor neurological outcome (CPC 3-5), while the EEG approach had no impact on patient prognosis and time to death. Our data suggest that cEEG does not confer any advantage over intermittent rEEG regarding outcome in patients with CA, and does not influence the time to death. Fatuzzo D. aut Beuchat I. aut Alvarez V. aut Novy J. aut Oddo M. aut Rossetti A.O. aut Resuscitation 132(2018-11), 29-32 132<29-32 2018 132 1 article serval SERVAL 700 1- Fatuzzo D. aut SERVAL 700 1- Beuchat I. aut SERVAL 700 1- Alvarez V. aut SERVAL 700 1- Novy J. aut SERVAL 700 1- Oddo M. aut SERVAL 700 1- Rossetti A.O. aut SERVAL 773 0- Resuscitation 132(2018-11), 29-32 132<29-32 2018 132 BK010053 XK010053 XK010000 SERVAL SERVAL SERVAL article