cam a22 4 4500 551328479 CHVBK 20201210092044.0 181213s2018 ne 00 0 eng|d 978-0-444-64044-4 print (NEBIS)011321398 (RERO)R008860606 YDX ger SzZuIDS NEBIS ETH-BIB rda s1ch rero 543.0285 23 Data analysis for Omic sciences methods and applications edited by Joaquim Jaumot, Carmen Bedia, Romà Tauler Amsterdam Elsevier [2018] xxiii, 706 Seiten Illustrationen Comprehensive analytical chemistry volume 82 82 (NEBIS)000490462 131040103 Includes bibliographical references and index 3.1. Hypothesis Formulation, Experimental Design, Sample Preparation and Analysis3.2. Preprocessing and Data Analysis ; 3.3. Results Evaluation and Biological interpretation ; 4. Future Trends ; Acknowledgements ; References ; Chapter Two: Experimental Approaches in Omic Sciences ; 1. Introduction ; 2. The Importance of the Biological Samples ; 3. Targeted and Untargeted Analytical Approaches in Omic Studies ; 4. Sample Preparation in Omics Studies ; 5. Analytical Technologies in Omic Sciences ; 5.1. Genomics, Epigenomics, and Transcriptomics ; 5.2. Proteomics ; 5.3. Metabolomics ; 6. Concluding Remarks 4.2. Array Normalization4.2.1. Main Steps ; 4.2.1.1. Background Correction ; 4.2.1.2. Normalization ; 4.2.1.3. Summarization ; 4.2.2. Methods ; 4.2.2.1. Robust Multichip Analysis ; 4.2.2.2. Probe Logarithmic Intensity Error ; 4.2.2.3. GC-RMA ; 4.3. Data Filtering ; 4.4. Batch Effect in Microarrays ; 5. Experimental Design for Microarray Experiments ; 5.1. Replication ; 5.1.1. Power and Sample Size ; 5.2. Pooling ; 5.3. Blocking Microarray Experiments ; 6. Statistical Analysis of Microarray Data ; 6.1. Class Comparison, Selecting Differentially Expressed Genes ; 6.1.1. Statistical Tests for Microarray Data 6.1.2. The Multiple Testing Problem and Proposed Solutions6.1.3. Volcano Plots ; 6.2. Class Prediction ; 6.3. Class Discovery ; 6.4. Biological Significance Analysis: Finding Meaning in Data ; 6.4.1. Pathway Analysis Methods ; 7. Microarray Bioinformatics ; 7.1. Software for Microarray Data Analysis ; 7.1.1. Open Source Software ; 7.1.2. The Bioconductor Project ; 7.1.3. Proprietary Software ; 7.2. Microarray Databases ; 8. Discussion and Conclusions ; Supplementary Materials ; Acknowledgements ; References ; Further Reading ; Chapter Four: RNA-Seq Data Analysis, Applications and Challenges ; 1. Introduction Front Cover ; Data Analysis for Omic Sciences: Methods and Applications ; Copyright ; Contents ; Contributors to Volume 82 ; Series Editorś Preface ; Preface ; Chapter One: Introduction to the Data Analysis Relevance in the Omic Era ; 1. Introduction to Omics ; 2. Data Analysis in the Omic Workflow ; 2.1. Molecular Hypothesis Formulation ; 2.2. Experimental Design ; 2.3. Sample Preparation and Instrumental Analysis ; 2.4. Preprocessing and Data Analysis ; 2.5. Results Evaluation and Biological Interpretation ; 3. Data Analysis Aspects Considered in This Volume REFERENCE / Questions & Answers bisacsh Biology Mathematical models fast Quantitative research fast ANWENDUNGEN DER MATHEMATIK IN DER CHEMIE ger (ETHUDK)000015777 ethudk AUFSATZSAMMLUNGEN (DOKUMENTENTYP) ger (ETHUDK)000009249 ethudk BIOLOGISCHE INFORMATIK UND COMPUTERANWENDUNG IN DER BIOLOGIE ger (ETHUDK)000050943 ethudk METABOLOMIK (BIOCHEMIE) ger (ETHUDK)000067331 ethudk MIKROARRAY TECHNOLOGIE (MOLEKULARGENETISCHE TECHNIKEN) ger (ETHUDK)000065802 ethudk NUKLEINSÄUREN-SEQUENZANALYSE ger (ETHUDK)000021862 ethudk TRANSKRIPTOMIK (MOLEKULARE GENETIK) ger (ETHUDK)000067332 ethudk Quantitative research Biology Mathematical models Biologie (RERO)A021006344 rero Modèles mathématiques (RERO)A021010554 rero Analyse quantitative (chimie) (RERO)A021021603 rero Bioinformatique (RERO)A021074447 rero Études diverses (RERO)A022249905 rero u METABOLOMIK (BIOCHEMIE) ger 577.121*1 nebis E1 u TRANSKRIPTOMIK (MOLEKULARE GENETIK) ger 577.214*1 nebis E1 u MIKROARRAY TECHNOLOGIE (MOLEKULARGENETISCHE TECHNIKEN) ger 577.21.088.3 nebis E1 u NUKLEINSÄUREN-SEQUENZANALYSE ger 577.113.5.088.5 nebis E1 u ANWENDUNGEN DER MATHEMATIK IN DER CHEMIE ger 51-79 nebis E1 u BIOLOGISCHE INFORMATIK UND COMPUTERANWENDUNG IN DER BIOLOGIE ger 57.087%519.68 nebis E1 u AUFSATZSAMMLUNGEN (DOKUMENTENTYP) ger (011.4) nebis E1 u METABOLOMICS (BIOCHEMISTRY) eng 577.121*1 nebis E1 u MÉTABOLOMIQUE (BIOCHIMIE) fre 577.121*1 nebis E1 u TRANSCRIPTOMICS (MOLECULAR GENETICS) eng 577.214*1 nebis E1 u TRANSCRIPTOMIQUE (GÉNÉTIQUE MOLÉCULAIRE) fre 577.214*1 nebis E1 u MICROARRAY TECHNOLOGY (MOLECULAR GENETIC TECHNIQUES) eng 577.21.088.3 nebis E1 u TECHNOLOGIE À PUCE (TECHNIQUES GÉNÉTIQUES MOLÉCULAIRES) fre 577.21.088.3 nebis E1 u ACIDES NUCLÉIQUES/ANALYSES DES SEQUENCES fre 577.113.5.088.5 nebis E1 u NUCLEIC ACIDS/SEQUENCE ANALYSIS eng 577.113.5.088.5 nebis E1 u APPLICATIONS OF MATHEMATICS IN CHEMISTRY eng 51-79 nebis E1 u APPLICATIONS DES MATHÉMATIQUES À LA CHIMIE fre 51-79 nebis E1 u BIOLOGICAL INFORMATICS AND COMPUTER APPLICATIONS IN BIOLOGY eng 57.087%519.68 nebis E1 u BIOINFORMATIQUE ET APPLICATIONS INFORMATIQUES EN BIOLOGIE fre 57.087%519.68 nebis E1 u COLLECTIONS OF ESSAYS (TYPE OF DOCUMENT) eng (011.4) nebis E1 u COLLECTIONS D'ARTICLES ET D'ESSAIS (TYPE DE DOCUMENT) fre (011.4) nebis E1 Jaumot Joaquim Herausgeber edt Bedia Carmen Herausgeber edt Tauler Romà Herausgeber edt Comprehensive analytical chemistry 82 (RERO)000602158 BK020000 XK020000 XK020000 E01-OS-ML-2018 nebis EO 041 E01-20181217 031 E01-20181217 047 E01-20181217 RERO RE61014 RE61014 RE610140028 BSCA 97/82 Vol. 82 Classé sous : Compr.Anal.Chem NEBIS UFBI UFBI ULGEZ ZS (FBI J) NEBIS E16 E16 RH C 2057: 82 NEBIS 490 0- Comprehensive analytical chemistry volume 82 82 (NEBIS)000490462 131040103 NEBIS 700 1- Jaumot Joaquim Herausgeber edt NEBIS 700 1- Bedia Carmen Herausgeber edt NEBIS 700 1- Tauler Romà Herausgeber edt RERO 490 1- Comprehensive analytical chemistry vol. 82 RERO 700 1- Bedia Carmen (IDREF)233053352 RERO 700 1- Jaumot Joaquim (IDREF)233053077 RERO 700 1- Tauler i Ferré Romà (RERO)A027676673 RERO 830 -- Comprehensive analytical chemistry 82 (RERO)000602158 NEBIS EAD50 EBI01 E16 https://opac.nebis.ch/objects/pdf03/e16_978-0-444-64044-4_01.pdf Titelblatt und Inhaltsverzeichnis VIEW pdf