cad a22 4500 551414472 20190411032215.0 cr unu---uuuuu 181214e20190101xx s 000 0 eng 10.5167/uzh-159307 doi 10.2463/mrms.mp.2018-0004 doi (ZORA)oai:www.zora.uzh.ch:159307 610 ddc 30416178 pmid Diffusion Tensor Imaging of the Brachial Plexus: A Comparison between Readout-segmented and Conventional Single-shot Echo-planar Imaging [Elektronische Daten] [Michael J Ho, Alexander Ciritsis, Andrei Manoliu, Bram Stieltjes, Magda Marcon, Gustav Andreisek, Felix Pierre Kuhn] openAccess eu-repo PURPOSE Diffusion tensor imaging (DTI) adds functional information to morphological magnetic resonance neurography (MRN) in the assessment of the brachial nerve plexus. To determine the most appropriate pulse sequence in scan times suited for diagnostic imaging in clinical routine, we compared image quality between simultaneous multi-slice readout-segmented (rs-DTI) and conventional single-shot (ss-DTI) echo-planar imaging techniques. METHODS Institutional Review Board (IRB) approved study including 10 healthy volunteers. The supraclavicular brachial plexus, covering the nerve roots and trunks from C5 to C7, was imaged on both sides with rs-DTI and ss-DTI. Both sequences were acquired in scan times <7 min with b-values of 900 s/mm and with isotropic spatial resolution. RESULTS In rs-DTI image, the overall quality was significantly better and distortion artifacts were significantly lower (P = 0.001-0.002 and P = 0.001-0.002, respectively) for both readers. In ss-DTI, a trend toward lower degree of ghosting and motion artifacts was elicited (reader 1, P = 0.121; reader 2, P = 0.264). No significant differences between the two DTI techniques were found for signal-to-noise ratios (SNR), contrast-to-noise ratios (CNR) and fractional anisotropy (FA) (P ≥ 0.475, P ≥ 0.624, and P ≥ 0.169, respectively). Interreader agreement for all examined parameters and all sequences ranged from intraclass correlation coefficient (ICC) 0.064 to 0.905 and Kappa 0.40 to 0.851. CONCLUSION Incomparable acquisition times rs-DTI showed higher image quality and less distortion artifacts than ss-DTI. The trend toward a higher degree of ghosting and motion artifacts in rs-DTI did not deteriorate image quality to a significant degree. Thus, rs-DTI should be considered for functional MRN of the brachial plexus. Clinic for Diagnostic and Interventional Radiology zora Ho Michael J. joint author Ciritsis Alexander joint author Manoliu Andrei joint author Stieltjes Bram joint author Marcon Magda joint author Andreisek Gustav joint author Kuhn Felix Pierre joint author Magnetic Resonance in Medical Sciences 18(2):150-157 https://www.zora.uzh.ch/id/eprint/159307/1/advpub_mp.2018-0004.pdf text/html WWW-Backlink auf das Repository 1 Journal Article PeerReviewed zora ZORA 856 40 https://www.zora.uzh.ch/id/eprint/159307/1/advpub_mp.2018-0004.pdf text/html WWW-Backlink auf das Repository ZORA 700 1- Ho Michael J. joint author ZORA 700 1- Ciritsis Alexander joint author ZORA 700 1- Manoliu Andrei joint author ZORA 700 1- Stieltjes Bram joint author ZORA 700 1- Marcon Magda joint author ZORA 700 1- Andreisek Gustav joint author ZORA 700 1- Kuhn Felix Pierre joint author ZORA 773 0- Magnetic Resonance in Medical Sciences 18(2):150-157 BK010053 XK010053 XK010000 ZORA ZORA ZORA Journal Article openAccess