cad a22 4500 551468106 20190902071916.0 cr unu---uuuuu 181215e20190901xx s 000 0 eng 10.5167/uzh-159400 doi 10.1007/s00345-018-2589-8 doi (ZORA)oai:www.zora.uzh.ch:159400 610 ddc 30511211 pmid Ho:YAG laser lithotripsy in non-contact mode: optimization of fiber to stone working distance to improve ablation efficiency [Elektronische Daten] [Vincent De Coninck, Etienne Xavier Keller, Paul Chiron, Laurian Dragos, Esteban Emiliani, Steeve Doizi, Laurent Berthe, Olivier Traxer] closedAccess eu-repo PURPOSE To evaluate how variable working distances between the laser fiber and the stone influence ablation volume. METHODS A laser fiber was fixed on a robotic arm perpendicular to an artificial stone. A single laser pulse was triggered at different working distances (0-2.0mm in 0.2mm increments) between the distal fiber tip and the stone. To achieve a measurable impact, pulse energy was set to 2 and 3J, with either short or long pulse duration. Ablation volume was calculated with an optical microscope. Experiments were repeated five times for each setting. RESULTS Highest ablation volume was observed with a long pulse of 3J at a working distance of 0.4mm between the laser fiber and the stone surface (p value<0.05). At 2J, the highest ablation volume was noticed with a short pulse in contact mode. However, ablation volume of the latter was not significantly greater than with a long pulse of 2J at a working distance of 0.4mm (p value>0.05). Compared to lithotripsy in contact mode, triggering a single long pulse at 0.4mm increased ablation volume by 81% (p value=0.016) at 2J and by 89% (p value=0.034) at 3 J. CONCLUSIONS For Ho:YAG laser lithotripsy, ablation volume may be higher in non-contact mode using long pulses, rather than in direct contact to the stone. Findings of the current study support the need of further studies of lithotripsy in non-contact mode. Urological Clinic zora De Coninck Vincent joint author Keller Etienne Xavier joint author Chiron Paul joint author Dragos Laurian joint author Emiliani Esteban joint author Doizi Steeve joint author Berthe Laurent joint author Traxer Olivier joint author World Journal of Urology 37(9):1933-1939 https://www.zora.uzh.ch/id/eprint/159400/1/DeConinck2018_Article_HoYAGLaserLithotripsyInNon-con.pdf text/html WWW-Backlink auf das Repository 1 Journal Article PeerReviewed zora ZORA 856 40 https://www.zora.uzh.ch/id/eprint/159400/1/DeConinck2018_Article_HoYAGLaserLithotripsyInNon-con.pdf text/html WWW-Backlink auf das Repository ZORA 700 1- De Coninck Vincent joint author ZORA 700 1- Keller Etienne Xavier joint author ZORA 700 1- Chiron Paul joint author ZORA 700 1- Dragos Laurian joint author ZORA 700 1- Emiliani Esteban joint author ZORA 700 1- Doizi Steeve joint author ZORA 700 1- Berthe Laurent joint author ZORA 700 1- Traxer Olivier joint author ZORA 773 0- World Journal of Urology 37(9):1933-1939 BK010053 XK010053 XK010000 ZORA ZORA ZORA Journal Article closedAccess