caa a22 4500 555159248 CHVBK 20200627055645.0 cr unu---uuuuu 190202e201902 xx s 000 0 eng 10.1038/s41371-018-0116-4 doi (SERVAL)BIB_A7AAE2B25C81 30283088 pmid 000458500900005 isiid Ten-year incidence of hypertension in a Swiss population-based sample Incidence of hypertension in Switzerland [Elektronische Daten] [ASQ Fidalgo, P. Vollenweider, P. Marques-Vidal] Few studies assessed incidence and determinants of hypertension. We assessed the incidence and determinants of hypertension in a cohort of healthy adults aged 35-75 years living in Lausanne, Switzerland. Baseline data were collected from 2003 to 2006. Follow-ups were conducted in 2009-2012 and 2014-2017. Incident hypertension, defined as a systolic BP ≥140 mm Hg or a diastolic BP ≥90 mm Hg or anti-hypertensive medication, was assessed at 1) second follow-up only; 2) first and/or second follow-up. After 10.9 years, incident hypertension was 26.8% (analysis 1, N = 3299) and 30.3% (analysis 2, N = 3728). After multivariate adjustment, the variables associated with increased hypertension incidence were male gender [incident-rate ratio (IRR) and (95% confidence interval)]: 1.20 (1.07-1.35) and 1.24 (1.13-1.37) for analyses 1 and 2, respectively; increasing age (p for trend &lt; 0.001) and body mass index (p for trend &lt; 0.001) and history of cardiovascular disease (CVD). Being physically active was negatively associated with incident hypertension: 0.88 (0.78-0.98) and 0.92 (0.83-1.01) for analyses 1 and 2, respectively. Except for male gender, these associations remained after adjusting for baseline BP levels, with incident rate ratios for physical activity of 0.86 (0.77-0.96) and 0.91 (0.83-0.99) for analyses 1 and 2, respectively. No association was found for education, alcohol consumption or smoking status. We conclude that over 10.9 years, between 1/4 and 1/3 of the Swiss population aged 35-75 developed hypertension. Male gender, history of CVD, increasing age and higher BMI increase the risk of hypertension, while being physically active reduces the risk. Fidalgo ASQ aut Vollenweider P. aut Marques-Vidal P. aut Journal of human hypertension 33/2(2019-02), 115-122 33:2<115-122 2019 33 BK010053 XK010053 XK010000 1 article serval SERVAL SERVAL SERVAL article SERVAL 700 1- Fidalgo ASQ aut SERVAL 700 1- Vollenweider P. aut SERVAL 700 1- Marques-Vidal P. aut SERVAL 773 0- Journal of human hypertension 33/2(2019-02), 115-122 33:2<115-122 2019 33