naa a22 4500 555243915 20190205064556.0 cr unu---uuuuu 190205e20181005xx s 000 0 eng 1424-8247 10.3390/ph11040098 doi (BORIS)oai:boris.unibe.ch:122994 610 ddc 30301142 pmid Yilmaz Bahtiyar Gut Microbiota and Iron: The Crucial Actors in Health and Disease [Elektronische Daten] [Bahtiyar Yilmaz, Hai Li] publishedVersion openAccess eu-repo Iron (Fe) is a highly ample metal on planet earth (~35% of the Earth's mass) and is particularly essential for most life forms, including from bacteria to mammals. Nonetheless, iron deficiency is highly prevalent in developing countries, and oral administration of this metal is so far the most effective treatment for human beings. Notably, the excessive amount of unabsorbed iron leave unappreciated side effects at the highly interactive host⁻microbe interface of the human gastrointestinal tract. Recent advances in elucidating the molecular basis of interactions between iron and gut microbiota shed new light(s) on the health and pathogenesis of intestinal inflammatory diseases. We here aim to present the dynamic modulation of intestinal microbiota by iron availability, and conversely, the influence on dietary iron absorption in the gut. The central part of this review is intended to summarize our current understanding about the effects of luminal iron on host⁻microbe interactions in the context of human health and disease. Li Hai joint author Pharmaceuticals 1424-8247 https://boris.unibe.ch/122994/1/pharmaceuticals-11-00098.pdf text/html WWW-Backlink auf das Repository 1 info:eu-repo/semantics/article boris PeerReviewed boris peerstatus BORIS 856 40 https://boris.unibe.ch/122994/1/pharmaceuticals-11-00098.pdf text/html WWW-Backlink auf das Repository BORIS 100 1- Yilmaz Bahtiyar BORIS 700 1- Li Hai joint author BORIS 773 0- Pharmaceuticals 1424-8247 BK010053 XK010053 XK010000 BORIS BORIS BORIS info:eu-repo/semantics/article openAccess