cam a22 5 4500 569358175 CHVBK 20201009220401.0 m d cr |n |||||||| 190413s2019 gw |||| s 0 0|eng d 978-3-030-00710-2 978-3-030-00709-6 (print) 978-3-030-00711-9 (print) 10.1007/978-3-030-00710-2 doi (SERSOL)ssj0002136978 (WaSeSS)ssj0002136978 WaSeSS RS380 RS190-210 TDCW bicssc MED072000 bisacsh 615.19 23 Pharmaceutical Biotechnology [Elektronische Daten] Fundamentals and Applications edited by Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm 5th ed. 2019. Cham Springer International Publishing Imprint: Springer 2019 1 online resource (XXIII, 653 p. 246 illus., 227 illus. in color.) online resource text txt rdacontent/ger computer c rdamedia/ger online resource cr rdacarrier/ger text file PDF rda Molecular Biotechnology -- Biophysical and biochemical analysis of recombinant proteins -- Production and downstream processing of biotech products -- Formulation of biotech products, including biopharmaceutical considerations -- Pharmacokinetics and pharmacodynamics of peptide and protein drugs -- Immunogenicity of pharmaceutical proteins -- General considerations of monoclonal antibodies from structure to therapeutic application -- Genomics, Other "Omics" Technologies, Personalized Medicine and Additional Biotechnology-Related Techniques -- Dispensing biotechnology products: handling, professional education and product information -- Economic considerations in medical biotechnology -- Regulatory framework for biosimilars -- Vaccines -- Oligonucleotides and siRNA -- Gene therapy -- Stem cell technology -- Therapeutic Applications.-Endocrinology -- Insulin -- Follicle-stimulating hormone -- Growth hormone -- Cardiovascular and Respiratory Applications -- Recombinant coagulation factors and thrombolytics -- Recombinant human deoxyribonuclease -- Oncology -- Monoclonal antibodies in oncology -- Hematopoetic growth factors -- Inflammation and Immunemodulation -- Monoclonal antibodies in transplantation -- Monoclonal antibodies and antibody-based therapeutics in anti-inflammatory therapy -- Interferons and interleukins -- Anti-infectious diseases -- Monoclonal antibodies -- Enzyme replacement therapy. Lizenzbedingungen können den Zugang einschränken. License restrictions may limit access. This introductory text explains both the basic science and the applications of biotechnology derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those who did not receive formal training in this field. Pharmaceutical Biotechnology: Fundamentals and Applications, Fifth Edition completely updates the previous edition, and includes additional coverage on newer approaches such as oligonucleotides, mi/siRNA, gene therapy and advanced therapeutics. Daan J.A. Crommelin is Professor Emeritus Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences at Utrecht University, Utrecht, The Netherlands and Adjunct Professor in the Department of Pharmaceutics and Pharmaceutical Chemistry at the University of Utah, Salt Lake City, UT, USA Robert D. Sindelar is Professor and former Dean Faculty of Pharmaceutical Sciences and The Centre for Health Evaluation & Outcomes Sciences (CHEOS), The University of British Columbia (UBC), Vancouver, BC, Canada and President of the Global Drug Commercialization Centre (GDCC)-China and Vice-President GDCC-worldwide, Chengdu, China Bernd Meibohm is Professor of Pharmaceutical Sciences and Associate Dean for Research and Graduate Programs at the University of Tennessee Health Science Center, College of Pharmacy, Memphis, TN, USA. Pharmaceutical technology Biomedical engineering Crommelin Daan J. A. editor edt http://id Sindelar Robert D. editor edt http://id Meibohm Bernd editor edt http://id SpringerLink (Online service) Printed edition 9783030007096 Printed edition 9783030007119 https://link.springer.com/10.1007/978-3-030-00710-2 Uni Basel: Volltext https://link.springer.com/10.1007/978-3-030-00710-2 Uni Bern: Volltext BK020053 XK020053 XK020000 Springer Biomedical and Life Sciences eBooks 2019 English/International E-Books von 360MarcUpdates TDC thema IDSBB A145 A145 145VT NELA1451907 IDSBB B405 B405 405VT NELB4051907 IDSBB 700 1- Crommelin Daan J. A. editor edt http://id IDSBB 700 1- Sindelar Robert D. editor edt http://id IDSBB 700 1- Meibohm Bernd editor edt http://id IDSBB 710 2- SpringerLink (Online service) IDSBB 776 08 Printed edition 9783030007096 IDSBB 776 08 Printed edition 9783030007119 IDSBB 856 40 https://link.springer.com/10.1007/978-3-030-00710-2 Uni Basel: Volltext IDSBB 856 40 https://link.springer.com/10.1007/978-3-030-00710-2 Uni Bern: Volltext SWISSBIB 311274331