Meniscal allograft transplantation in a symptomatic meniscal deficient knee: a systematic review

Verfasser / Beitragende:
[Nick Smith, Nicola MacKay, Matthew Costa, Tim Spalding]
Ort, Verlag, Jahr:
2015
Enthalten in:
Knee Surgery, Sports Traumatology, Arthroscopy, 23/1(2015-01-01), 270-279
Format:
Artikel (online)
ID: 605456151
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024 7 0 |a 10.1007/s00167-014-3310-0  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00167-014-3310-0 
245 0 0 |a Meniscal allograft transplantation in a symptomatic meniscal deficient knee: a systematic review  |h [Elektronische Daten]  |c [Nick Smith, Nicola MacKay, Matthew Costa, Tim Spalding] 
520 3 |a Purpose: The primary objective of this study was to perform an updated systematic review and meta-analysis of meniscal allograft transplantation using patient reported outcome measures at final follow-up as the outcome tool. The secondary objective was to provide an up to date review of the indications, associated procedures, operative technique, rehabilitation, failures, complications, radiological outcomes, and graft healing. Methods: Medline, Embase and CENTRAL databases, trials registries, and Web-of Science were searched for studies using pre-defined eligibility criteria. Included studies were reviewed with Lysholm, International Knee Documentation Committee (IKDC) and Tegner scores, failures and complications pooled. Studies were also qualitatively assessed. Results: There were 1,332 patients (1,374 knees) in 35 studies eligible for analysis. The mean follow-up was 5.1years. Across all studies, Lysholm scores improved from 55.7 to 81.3, IKDC scores from 47.0 to 70.0, and Tegner activity scores from 3.1 to 4.7 between pre-operative and final follow-up assessments, respectively. The mean failure rate across all studies was 10.6% at 4.8years, and complication rate was 13.9% at 4.7years. There is a high risk of bias across the studies due to study design and missing outcomes. Conclusion: Based on current evidence, meniscal allograft transplantation appears to be an effective intervention for patients with a symptomatic meniscal deficient knee. This should ideally be confirmed with a randomised controlled trial. There is not currently enough evidence to determine whether it is chondroprotective. 
540 |a European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA), 2014 
690 7 |a Meniscal allograft transplantation  |2 nationallicence 
690 7 |a Systematic review  |2 nationallicence 
690 7 |a Meniscectomy  |2 nationallicence 
690 7 |a Patient reported outcome measures  |2 nationallicence 
700 1 |a Smith  |D Nick  |u Clinical Sciences Research Laboratories, University of Warwick, Clifford Bridge Road, CV2 2DX, Coventry, UK  |4 aut 
700 1 |a MacKay  |D Nicola  |u Western Infirmary Glasgow, Dumbarton Road, G11 6NT, Glasgow, UK  |4 aut 
700 1 |a Costa  |D Matthew  |u Clinical Trials Unit, Warwick Medical School, University of Warwick, CV4 7AL, Coventry, UK  |4 aut 
700 1 |a Spalding  |D Tim  |u University Hospitals Coventry and Warwickshire, 5th floor UHCW, Clifford Bridge Road, CV2 2DX, Coventry, UK  |4 aut 
773 0 |t Knee Surgery, Sports Traumatology, Arthroscopy  |d Springer Berlin Heidelberg  |g 23/1(2015-01-01), 270-279  |x 0942-2056  |q 23:1<270  |1 2015  |2 23  |o 167 
856 4 0 |u https://doi.org/10.1007/s00167-014-3310-0  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Smith  |D Nick  |u Clinical Sciences Research Laboratories, University of Warwick, Clifford Bridge Road, CV2 2DX, Coventry, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a MacKay  |D Nicola  |u Western Infirmary Glasgow, Dumbarton Road, G11 6NT, Glasgow, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Costa  |D Matthew  |u Clinical Trials Unit, Warwick Medical School, University of Warwick, CV4 7AL, Coventry, UK  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Spalding  |D Tim  |u University Hospitals Coventry and Warwickshire, 5th floor UHCW, Clifford Bridge Road, CV2 2DX, Coventry, UK  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Knee Surgery, Sports Traumatology, Arthroscopy  |d Springer Berlin Heidelberg  |g 23/1(2015-01-01), 270-279  |x 0942-2056  |q 23:1<270  |1 2015  |2 23  |o 167