caa a22 4500 605456364 CHVBK 20210128100217.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00167-014-3314-9 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3314-9 Patients achieved greater range of movement when using high-flexion implants [Elektronische Daten] [Canfeng Li, Yi Zeng, Bin Shen, Jing Yang, Zongke Zhou, Pengde Kang, Fuxing Pei] Purpose: NexGen Legacy Posterior Stabilized high-flexion prostheses (LPS-Flex) have been popularized as an alternative to NexGen standard prostheses (LPS) in total knee arthroplasty (TKA). Advocates of this new generation prosthesis suggest improved postoperative knee flexion. The purpose of this study was to summarize the best evidence for comparing the range of motion (ROM) and functional outcomes of LPS-Flex prostheses and LPS in TKA. Methods: Electronic databases were systematically searched to identify relevant randomized controlled trials (RCTs). The last date for our research was July 2014. Our search strategy was followed the requirements of the Cochrane Library Handbook. The methodological quality was assessed, and the data were extracted independently by two authors. Results: Nine studies that included 978 knees met our inclusion criteria for review. The results showed that there was larger postoperative ROM (1.62, 95% CI 0.52-2.72) in the LPS-Flex group than in the LPS group. There was not a statistically significant difference in the clinical functional scores and complications between the LPS-Flex group and the LPS group in TKA. The pooled mean differences were as follows: total KSS, −0.64 (95% CI −1.41 to 0.13); functional KSS, −0.53 (95% CI −1.51 to 0.45); HSS, 0.23 (95% CI −0.87 to 1.33); complications, 0.49 (95% CI 0.20-1.24); and radiolucent lines, 1.56 (95% CI 0.68-3.55). Conclusions: The preliminary results indicate that the NexGen LPS-Flex prosthesis provides an alternative to the NexGen LPS prosthesis, with greater range of motion and without severe complications or radiographic outcomes. The clinical advantages were not shown in the KSS or the HSS. Thus, the selection of a high-flexion prosthesis should depend on the characteristics of the patient, particularly high motivation and poor preoperative ROM. The potential benefits in the medium- and long-term outcomes require confirmation by larger, multicenter and well-conducted RCTs. Level of evidence: Therapeutic study, Level I. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA), 2014 High-flexion prosthesis nationallicence Standard prosthesis nationallicence Range of motion nationallicence Total knee arthroplasty nationallicence Li Canfeng The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Zeng Yi The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Shen Bin The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Yang Jing The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Zhou Zongke The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Kang Pengde The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Pei Fuxing The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1598-1609 0942-2056 23:6<1598 2015 23 167 https://doi.org/10.1007/s00167-014-3314-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3314-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Li Canfeng The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 700 1- Zeng Yi The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 700 1- Shen Bin The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 700 1- Yang Jing The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 700 1- Zhou Zongke The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 700 1- Kang Pengde The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 700 1- Pei Fuxing The Orthopedic Department, West China Hospital, Sichuan University, Chengdu, China aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1598-1609 0942-2056 23:6<1598 2015 23 167