caa a22 4500 605456488 CHVBK 20210128100218.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00167-014-3301-1 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3301-1 The influence of body mass index on the outcomes of primary total knee arthroplasty [Elektronische Daten] [Hai-bo Si, Yi Zeng, Bin Shen, Jing Yang, Zong-ke Zhou, Peng-de Kang, Fu-xing Pei] Purpose: The body mass index (BMI) is widely recognized as a prognostic factor in multiple operations; however, the relationship between the BMI and outcomes following total knee arthroplasty (TKA) is extensively debated. We aimed to evaluate the effect of the BMI at different cutoff values on the outcomes following primary TKA. Methods: Electronic databases (PubMed/Medline, CENTRAL, Embase and Web of Science) were systematically searched for studies investigating the association between the BMI and outcomes following primary TKA. Two investigators independently reviewed studies for eligibility, assessed the study quality using the Newcastle-Ottawa Scale and extracted the data. A meta-analysis was performed using Review Manager software. Results: Twenty-eight articles including a total of 20,988 TKAs were identified. The postoperative Knee Society Score appeared to trend lower in obese (BMI≥30kg/m2) patients than in non-obese (BMI<30kg/m2) patients. The meta-analysis showed that revision with follow-up ≥5years, any infection, superficial infection and deep vein thrombosis occurred statistically more frequently in obese patients, whereas a deep infection occurred statistically more frequently in morbidly obese (BMI≥40kg/m2) patients than in non-obese patients. No differences in aseptic loosening with follow-up ≥5years, pulmonary embolism and perioperative mortality rates were found between obese and non-obese patients. Conclusions: Patients with a BMI≥30kg/m2 are at a higher risk of lower functional scores and developing complications following primary TKA. It appears reasonable to encourage obese patients to lose weight before selective TKA. Level of evidence: Prognostic study, Level III. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA), 2014 Total knee arthroplasty nationallicence Body mass index nationallicence Obesity nationallicence Systematic review nationallicence Meta-analysis nationallicence Si Hai-bo Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Zeng Yi Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Shen Bin Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Yang Jing Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Zhou Zong-ke Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Kang Peng-de Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Pei Fu-xing Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1824-1832 0942-2056 23:6<1824 2015 23 167 https://doi.org/10.1007/s00167-014-3301-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3301-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Si Hai-bo Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 700 1- Zeng Yi Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 700 1- Shen Bin Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 700 1- Yang Jing Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 700 1- Zhou Zong-ke Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 700 1- Kang Peng-de Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 700 1- Pei Fu-xing Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, 37# Guoxue Road, 610041, Chengdu, People's Republic of China aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1824-1832 0942-2056 23:6<1824 2015 23 167