caa a22 4500 605456534 CHVBK 20210128100218.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00167-014-3359-9 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3359-9 No clinical benefit of titanium nitride coating in cementless mobile-bearing total knee arthroplasty [Elektronische Daten] [Ruud van Hove, Richard Brohet, Barend van Royen, Peter Nolte] Purpose: Titanium nitride (TiN) coating of cobalt-chromium-molybdenum (CoCrMo) implants has shown to improve the biomechanical properties of the implant surface and to reduce adhesive wear in vitro. It is yet unknown whether TiN coating of total knee prosthesis (TKP) affects the postoperative clinical outcome of total knee arthroplasty (TKA). Methods: In a double-blind randomized controlled clinical trial, 101 patients received an uncemented mobile-bearing CoCrMo TKP, either TiN coated or uncoated. Primary outcome measure visual analogue scale (VAS) score for pain, and secondary outcome measures Knee Society Score (KSS), revision rate and adverse events, range of motion of the knee as well as knee circumference and knee skin temperature were assessed 6weeks, 6months, 1year and 5years postoperative. Repeated measures analysis was used to evaluate the postoperative outcome measures over time. Results: There was no difference between the two groups in VAS score, KSS, revision rate, range of motion of the knee, knee circumference and knee skin temperature. There were no adverse events that could be related to the TiN coating. Conclusions: TiN-coated TKP does not influence the postoperative outcome of uncemented mobile-bearing TKA regarding postoperative pain, revision rate, range of motion, swelling and temperature of the knee. Therefore, TiN coating of CoCrMo TKP has no clinical benefit on the outcome of cementless mobile-bearing TKA. Level of evidence: Therapeutic study, Level I. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA), 2014 Titanium nitride nationallicence Mobile-bearing total knee arthroplasty nationallicence Postoperative outcome nationallicence van Hove Ruud Department of Orthopaedics, Spaarne Hospital, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands aut Brohet Richard Research Center Linnaeus Institute, Spaarne Hospital, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands aut van Royen Barend Department of Orthopaedics, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands aut Nolte Peter Department of Orthopaedics, Spaarne Hospital, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1833-1840 0942-2056 23:6<1833 2015 23 167 https://doi.org/10.1007/s00167-014-3359-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3359-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van Hove Ruud Department of Orthopaedics, Spaarne Hospital, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands aut NATIONALLICENCE 700 1- Brohet Richard Research Center Linnaeus Institute, Spaarne Hospital, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands aut NATIONALLICENCE 700 1- van Royen Barend Department of Orthopaedics, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Nolte Peter Department of Orthopaedics, Spaarne Hospital, Spaarnepoort 1, 2134 TM, Hoofddorp, The Netherlands aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1833-1840 0942-2056 23:6<1833 2015 23 167