caa a22 4500 605456542 CHVBK 20210128100218.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00167-015-3557-0 doi (NATIONALLICENCE)springer-10.1007/s00167-015-3557-0 Clinical outcomes after high-flex versus conventional total knee arthroplasty [Elektronische Daten] [Alisara Arirachakaran, Tana Wande, Kwanchai Pituckhanotai, Pradit Predeeprompan, Jatupon Kongtharvonskul] Purpose: To compare clinical outcomes after high-flex versus conventional total knee arthroplasty (TKA). Methods: A systematic review and meta-regression were performed to compare post-operative outcomes between the two types of prostheses. Relevant randomized controlled trials were identified from MEDLINE and Scopus up to November, 2014. Results: Fourteen of 369 studies were eligible; 14, 7, 6, 5, 3, 12 and 7 studies were included in the pooling of maximum knee flexion, Knee Society Knee Score (KS), Knee Society Function Score (FS), Hospital for Special Surgery score (HSS), short-form (SF) physical activity score, post-operative complications (DVT, fractures, infection) and revision TKA, respectively. The high-flex TKA had 1.97° [95% confidence interval (CI) 0.37, 3.57], −0.86 (95% CI −1.65, 0.07) and −1.34 (−2.57, −0.11) higher mean maximum knee flexion, KS and FS when compared to conventional TKA. However, there were non-significant differences in HSS, SF-36 (physical), complications and revision TKA. Conclusion: This study suggests that there are improvements in post-operative knee range of motion and knee scores in high-flex TKA implants when compared to conventional TKA implants; however, the difference was very small and therefore might not have any clinical impact. Therefore, conventional TKA can be used as a substitute. However, cost-effective analysis should be performed to make appropriate selections in the future. There are no statistically significant differences in terms of HSS, quality of life, complications and revisions between the groups. Level of evidence: I. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA), 2015 High flex nationallicence Conventional nationallicence Total knee arthroplasty nationallicence Systematic review nationallicence Meta-regression nationallicence Flexion nationallicence Arirachakaran Alisara Orthopedics Department, Police General Hospital, Bangkok, Thailand aut Wande Tana Orthopedics Department, Police General Hospital, Bangkok, Thailand aut Pituckhanotai Kwanchai Orthopedics Department, Police General Hospital, Bangkok, Thailand aut Predeeprompan Pradit Orthopedics Department, Police General Hospital, Bangkok, Thailand aut Kongtharvonskul Jatupon Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1610-1621 0942-2056 23:6<1610 2015 23 167 https://doi.org/10.1007/s00167-015-3557-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-015-3557-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Arirachakaran Alisara Orthopedics Department, Police General Hospital, Bangkok, Thailand aut NATIONALLICENCE 700 1- Wande Tana Orthopedics Department, Police General Hospital, Bangkok, Thailand aut NATIONALLICENCE 700 1- Pituckhanotai Kwanchai Orthopedics Department, Police General Hospital, Bangkok, Thailand aut NATIONALLICENCE 700 1- Predeeprompan Pradit Orthopedics Department, Police General Hospital, Bangkok, Thailand aut NATIONALLICENCE 700 1- Kongtharvonskul Jatupon Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/6(2015-06-01), 1610-1621 0942-2056 23:6<1610 2015 23 167