Monitoring concussion in a knocked-out boxer by CSF biomarker analysis
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| 008 | 210128e20150901xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00167-014-3066-6 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00167-014-3066-6 | ||
| 245 | 0 | 0 | |a Monitoring concussion in a knocked-out boxer by CSF biomarker analysis |h [Elektronische Daten] |c [Sanna Neselius, Helena Brisby, Fredrik Granholm, Henrik Zetterberg, Kaj Blennow] |
| 520 | 3 | |a Concussion is common in many sports, and the incidence is increasing. The medical consequences after a sport-related concussion have received increased attention in recent years since it is known that concussions cause axonal and glial damage, which disturbs the cerebral physiology and makes the brain more vulnerable for additional concussions. This study reports on a knocked-out amateur boxer in whom cerebrospinal fluid (CSF) neurofilament light (NFL) protein, reflecting axonal damage, was used to identify and monitor brain damage. CSF NFL was markedly increased during 36weeks, suggesting that neuronal injury persists longer than expected after a concussion. CSF biomarker analysis may be valuable in the medical counselling of concussed athletes and in return-to-play considerations. Level of evidence IV | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a Concussion |2 nationallicence | |
| 690 | 7 | |a Traumatic brain injury (TBI) |2 nationallicence | |
| 690 | 7 | |a Mild traumatic brain injury |2 nationallicence | |
| 690 | 7 | |a Boxing |2 nationallicence | |
| 700 | 1 | |a Neselius |D Sanna |u Department of Orthopaedics, Sahlgrenska University Hospital, 413 45, Gothenburg, Sweden |4 aut | |
| 700 | 1 | |a Brisby |D Helena |u Department of Orthopaedics, Sahlgrenska University Hospital, 413 45, Gothenburg, Sweden |4 aut | |
| 700 | 1 | |a Granholm |D Fredrik |u Department of Emergency Medicine, Sundsvall County Hospital, Sundsvall, Sweden |4 aut | |
| 700 | 1 | |a Zetterberg |D Henrik |u Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden |4 aut | |
| 700 | 1 | |a Blennow |D Kaj |u Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden |4 aut | |
| 773 | 0 | |t Knee Surgery, Sports Traumatology, Arthroscopy |d Springer Berlin Heidelberg |g 23/9(2015-09-01), 2536-2539 |x 0942-2056 |q 23:9<2536 |1 2015 |2 23 |o 167 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00167-014-3066-6 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00167-014-3066-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Neselius |D Sanna |u Department of Orthopaedics, Sahlgrenska University Hospital, 413 45, Gothenburg, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Brisby |D Helena |u Department of Orthopaedics, Sahlgrenska University Hospital, 413 45, Gothenburg, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Granholm |D Fredrik |u Department of Emergency Medicine, Sundsvall County Hospital, Sundsvall, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zetterberg |D Henrik |u Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Blennow |D Kaj |u Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Knee Surgery, Sports Traumatology, Arthroscopy |d Springer Berlin Heidelberg |g 23/9(2015-09-01), 2536-2539 |x 0942-2056 |q 23:9<2536 |1 2015 |2 23 |o 167 | ||