Efficacy of intraarticular application of ketamine or ketamine-levobupivacaine combination on post-operative pain after arthroscopic meniscectomy
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| 024 | 7 | 0 | |a 10.1007/s00167-014-2962-0 |2 doi |
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| 245 | 0 | 0 | |a Efficacy of intraarticular application of ketamine or ketamine-levobupivacaine combination on post-operative pain after arthroscopic meniscectomy |h [Elektronische Daten] |c [Cengiz Isik, Abdullah Demirhan, Tevfik Yetis, Korgun Oktem, Hakan Sarman, Umit Tekelioglu, Turan Duran] |
| 520 | 3 | |a Purpose: To evaluate the efficacy of intraarticular injection of ketamine or ketamine plus levobupivacaine on post-operative analgesia in patients undergoing arthroscopic meniscectomy. Methods: A prospective, randomized, double-blind study was performed on 60 patients aged 18-65years who planned to undergo elective arthroscopic meniscectomy. The patients were divided into three groups: the ketamine group (n=20) received 1.0mg/kg of intraarticular ketamine in 20ml of normal saline, the ketamine-levobupivacaine group (n=20) received 0.5mg/kg of intraarticular ketamine plus 50.0mg of 0.25% levobupivacaine in 20ml of normal saline, and the control group (n=20) received 20ml of intraarticular normal saline. A visual analogue scale (VAS) was used to determine the efficacy of analgesia at 1, 2, 4, 6, 8, 12, and 24h post-operatively. Results: There were statistically significant differences in the median VAS scores among the three groups according to Bonferroni adjustment at all time points (p<0.01), with the exception of 6 and 24h post-operatively. The median VAS scores at 1, 2, and 4h post-operatively were higher in the control group than in the two treatment groups (p<0.001). The median VAS scores in the control group at 1, 2, 4, 6, 8, and 12h post-operatively and those in the ketamine group at 4, 8, and 12h post-operatively were significantly higher than those in the ketamine-levobupivacaine group (p<0.05). Conclusion: Intraarticular ketamine provides effective post-operative analgesia. Addition of intraarticular levobupivacaine to ketamine may provide better amelioration of pain after outpatient arthroscopic meniscectomy. Level of evidence: I. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2014 | ||
| 690 | 7 | |a Arthroscopic meniscectomy |2 nationallicence | |
| 690 | 7 | |a Intraarticular injection |2 nationallicence | |
| 690 | 7 | |a Ketamine |2 nationallicence | |
| 690 | 7 | |a Levobupivacaine |2 nationallicence | |
| 700 | 1 | |a Isik |D Cengiz |u Department of Orthopedics and Traumatology, Faculty of Medicine, Abant İzzet Baysal University Medical School, Abant İzzet Baysal University, 14280, Gölköy, Bolu, Turkey |4 aut | |
| 700 | 1 | |a Demirhan |D Abdullah |u Department of Anesthesiology and Reanimation, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey |4 aut | |
| 700 | 1 | |a Yetis |D Tevfik |u Department of Orthopedics and Traumatology, Bolu Izzet Baysal State Hospital, Bolu, Turkey |4 aut | |
| 700 | 1 | |a Oktem |D Korgun |u Department of Anesthesiology and Reanimation, Bolu Izzet Baysal State Hospital, Bolu, Turkey |4 aut | |
| 700 | 1 | |a Sarman |D Hakan |u Department of Orthopedics and Traumatology, Faculty of Medicine, Abant İzzet Baysal University Medical School, Abant İzzet Baysal University, 14280, Gölköy, Bolu, Turkey |4 aut | |
| 700 | 1 | |a Tekelioglu |D Umit |u Department of Anesthesiology and Reanimation, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey |4 aut | |
| 700 | 1 | |a Duran |D Turan |u Department of Orthopedics and Traumatology, Bolu Izzet Baysal State Hospital, Bolu, Turkey |4 aut | |
| 773 | 0 | |t Knee Surgery, Sports Traumatology, Arthroscopy |d Springer Berlin Heidelberg |g 23/9(2015-09-01), 2721-2726 |x 0942-2056 |q 23:9<2721 |1 2015 |2 23 |o 167 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00167-014-2962-0 |q text/html |z Onlinezugriff via DOI |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00167-014-2962-0 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Isik |D Cengiz |u Department of Orthopedics and Traumatology, Faculty of Medicine, Abant İzzet Baysal University Medical School, Abant İzzet Baysal University, 14280, Gölköy, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Demirhan |D Abdullah |u Department of Anesthesiology and Reanimation, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yetis |D Tevfik |u Department of Orthopedics and Traumatology, Bolu Izzet Baysal State Hospital, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Oktem |D Korgun |u Department of Anesthesiology and Reanimation, Bolu Izzet Baysal State Hospital, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sarman |D Hakan |u Department of Orthopedics and Traumatology, Faculty of Medicine, Abant İzzet Baysal University Medical School, Abant İzzet Baysal University, 14280, Gölköy, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tekelioglu |D Umit |u Department of Anesthesiology and Reanimation, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Duran |D Turan |u Department of Orthopedics and Traumatology, Bolu Izzet Baysal State Hospital, Bolu, Turkey |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Knee Surgery, Sports Traumatology, Arthroscopy |d Springer Berlin Heidelberg |g 23/9(2015-09-01), 2721-2726 |x 0942-2056 |q 23:9<2721 |1 2015 |2 23 |o 167 | ||