caa a22 4500 60545695X CHVBK 20210128100220.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00167-014-2975-8 doi (NATIONALLICENCE)springer-10.1007/s00167-014-2975-8 Intra- and inter-observer reliability of ten major histological scoring systems used for the evaluation of in vivo cartilage repair [Elektronische Daten] [Davide Bonasia, Antongiulio Marmotti, Alessandro Massa, Andrea Ferro, Davide Blonna, Filippo Castoldi, Roberto Rossi] Purpose: In the last two decades, many surgical techniques have been described for articular cartilage repair. Reliable histological scoring systems are fundamental tools to evaluate new procedures. Several histological scoring systems have been described, and these can be divided in elementary and comprehensive scores, according to the number of sub-items. The aim of this study was to test the inter- and intra-observer reliability of ten main scores used for the histological evaluation of in vivo cartilage repair. The authors tested the starting hypothesis that elementary scores would show superior intra- and inter-observer reliability compared with comprehensive scores. Methods: Fifty histological sections obtained from the trochlea of New Zealand Rabbit and stained with Safranin-O fast green were used. The histological sections were analysed by 4 observers: 2 experienced in cartilage histology and 2 inexperienced. Histological evaluations were performed at time 1 and time 2, separated by a 30-day interval. The following scores were used: Mankin, O'Driscoll, Pineda, Wakitani, Fortier, Selleres, ICRS, ICRSII, Oswestry (OsScore) and modified O'Driscoll. Intra- and inter-observer reliability were evaluated for each score. In addition, the pavement-ceiling effect and the Bland-Altman Coefficient of Repeatability were then evaluated for each sub-item of every score. Results: Intra-observer reliability was high for all observers in every score, even though the reliability was significantly lower for non-expert observers compared with expert counterparts. In terms of Coefficient of Repeatability, some scores performed better (O'Driscoll, Modified O'Driscoll and ICRSII) than others (Fortier, Seller). Inter-observer reliability was high for all observers in every score, but significantly lower for non-expert compared with expert observers. Conclusions: In expert hands, all the scores showed high intra- and inter-observer reliability, independently of the complexity. Although every score has advantages and disadvantages, ICRSII, O'Driscoll and Modified O'Driscoll scores should be preferred for the evaluation of in vivo cartilage repair in animal models. Springer-Verlag Berlin Heidelberg, 2014 Cartilage nationallicence Histology nationallicence Score nationallicence Reliability nationallicence Observer nationallicence Bonasia Davide AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut Marmotti Antongiulio AO Mauriziano "Umberto I”, Universita' degli Studi di Torino, Turin, Italy aut Massa Alessandro AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut Ferro Andrea AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut Blonna Davide AO Mauriziano "Umberto I”, Universita' degli Studi di Torino, Turin, Italy aut Castoldi Filippo AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut Rossi Roberto AO Mauriziano "Umberto I”, Universita' degli Studi di Torino, Turin, Italy aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/9(2015-09-01), 2484-2493 0942-2056 23:9<2484 2015 23 167 https://doi.org/10.1007/s00167-014-2975-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-2975-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bonasia Davide AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Marmotti Antongiulio AO Mauriziano "Umberto I”, Universita' degli Studi di Torino, Turin, Italy aut NATIONALLICENCE 700 1- Massa Alessandro AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Ferro Andrea AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Blonna Davide AO Mauriziano "Umberto I”, Universita' degli Studi di Torino, Turin, Italy aut NATIONALLICENCE 700 1- Castoldi Filippo AO Citta' della Salute e della Scienza, Azienda Ospedaliera CTO, Universita' degli Studi di Torino, Via Lamarmora 26, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Rossi Roberto AO Mauriziano "Umberto I”, Universita' degli Studi di Torino, Turin, Italy aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/9(2015-09-01), 2484-2493 0942-2056 23:9<2484 2015 23 167