caa a22 4500 60545731X CHVBK 20210128100222.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00167-014-2952-2 doi (NATIONALLICENCE)springer-10.1007/s00167-014-2952-2 The use of patient-specific instruments does not reduce blood loss during minimally invasive total knee arthroplasty? [Elektronische Daten] [Emmanuel Thienpont, Irina Grosu, Frederic Paternostre, Pierre-Emmanuel Schwab, Jean Yombi] Purpose: Blood loss can be substantial and will influence morbidity and mortality after total knee arthroplasty. This study evaluated whether patient-specific instruments (PSI) can reduce blood loss because the intramedullary canal is not opened during the procedure and whether hidden blood loss can be reduced by its use. Methods: Seventy-five patients operated with the Signature PSI technique were compared with a matched group operated with conventional instruments. Maximal drop in haemoglobin (Hb) and hematocrit (HTC) level were compared at day 2 and day 4. Transfusions were noted. Clinical outcomes like range of motion and knee society scores were studied as secondary outcomes. Results: No statistically significant difference for calculated blood loss, maximal drop in Hb or HTC and transfusions were found. No clinical differences in range of motion or knee society scores were observed. Conclusions: The use of PSI-assisted total knee arthroplasty (TKA) did not result in less blood loss compared with conventional minimally invasive TKA with tourniquet. No reduction in hidden blood loss was observed either. According to this study, the argument of reduced transfusion cost should not be used in cost-effectiveness calculations of PSI-assisted TKA. Level of evidence: III. Springer-Verlag Berlin Heidelberg, 2014 Patient-specific instruments nationallicence Blood loss nationallicence Transfusion nationallicence Total knee arthroplasty nationallicence Thienpont Emmanuel Department of Orthopedic Surgery, Cliniques Universitaires Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium aut Grosu Irina Department of Anesthesiology, Cliniques Universitaires Saint Luc, Brussels, Belgium aut Paternostre Frederic Department of Orthopedic Surgery, Cliniques Universitaires Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium aut Schwab Pierre-Emmanuel Department of Orthopedic Surgery, Cliniques Universitaires Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium aut Yombi Jean Department of Internal and Perioperative Medicine, Cliniques Universitaires Saint Luc, Brussels, Belgium aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/7(2015-07-01), 2055-2060 0942-2056 23:7<2055 2015 23 167 https://doi.org/10.1007/s00167-014-2952-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-2952-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Thienpont Emmanuel Department of Orthopedic Surgery, Cliniques Universitaires Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium aut NATIONALLICENCE 700 1- Grosu Irina Department of Anesthesiology, Cliniques Universitaires Saint Luc, Brussels, Belgium aut NATIONALLICENCE 700 1- Paternostre Frederic Department of Orthopedic Surgery, Cliniques Universitaires Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium aut NATIONALLICENCE 700 1- Schwab Pierre-Emmanuel Department of Orthopedic Surgery, Cliniques Universitaires Saint Luc, Av. Hippocrate 10, 1200, Brussels, Belgium aut NATIONALLICENCE 700 1- Yombi Jean Department of Internal and Perioperative Medicine, Cliniques Universitaires Saint Luc, Brussels, Belgium aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/7(2015-07-01), 2055-2060 0942-2056 23:7<2055 2015 23 167