caa a22 4500 605457484 CHVBK 20210128100223.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s00167-014-3191-2 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3191-2 Postarthroscopy analgesia using intraarticular levobupivacaine and intravenous dexketoprofen trometamol [Elektronische Daten] [Sevtap Sahin, Dilek Memiş, Erkan Celik, Necdet Sut] Purpose: The aim of this prospective study was to determine the efficacy of intraarticular levobupivacaine with and without intravenous dexketoprofen trometamol for postarthroscopy analgesia. Methods: Sixty patients who underwent arthroscopic knee surgery were randomly assigned to three treatment groups. When the surgical procedure was completed, patients received the following treatments: group I (n=20) patients received 20mL intraarticular normal saline and 2mL intravenous dexketoprofen trometamol (50mg); group II (n=20) patients received 20mL intraarticular 0.5% levobupivacaine (100mg) and 2mL intravenous normal saline; and group III (n=20) patients received 20mL intraarticular 0.5% levobupivacaine (100mg) and 2mL intravenous dexketoprofen trometamol (50mg). The visual analogue scale (VAS) was used, and the total analgesic consumption was assessed at 1, 2, 4, 6, 12, and 24h post-operatively. Results: The VAS scores at 1, 2, 4, 6, 12, and 24h post-operatively were significantly increased in group I and group II compared with group III (p<0.05). The average VAS score during the first 24h post-operatively was significantly lower in group III than in group I and group II (p<0.001). Total meperidine consumption was significantly lower in group III than in groups I and II (p<0.001). Conclusion: Intraarticular levobupivacaine with adjuvant intravenous dexketoprofen trometamol administration provided better pain relief and less analgesic requirement after arthroscopic knee surgery during the first 24h than that induced by dexketoprofen alone or levobupivacaine intraarticular alone. Level of evidence: II. Springer-Verlag Berlin Heidelberg, 2014 Arthroscopy nationallicence Post-operative analgesia nationallicence Post-operative pain nationallicence Dexketoprofen trometamol nationallicence Levobupivacaine nationallicence Sahin Sevtap Department of Anesthesiology and Reanimation, Trakya University Medical Faculty, 22030, Edirne, Turkey aut Memiş Dilek Department of Anesthesiology and Reanimation, Trakya University Medical Faculty, 22030, Edirne, Turkey aut Celik Erkan Department of Anesthesiology and Reanimation, Trakya University Medical Faculty, 22030, Edirne, Turkey aut Sut Necdet Department of Biostatistics, Trakya University Medical Faculty, Edirne, Turkey aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/12(2015-12-01), 3516-3522 0942-2056 23:12<3516 2015 23 167 https://doi.org/10.1007/s00167-014-3191-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3191-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sahin Sevtap Department of Anesthesiology and Reanimation, Trakya University Medical Faculty, 22030, Edirne, Turkey aut NATIONALLICENCE 700 1- Memiş Dilek Department of Anesthesiology and Reanimation, Trakya University Medical Faculty, 22030, Edirne, Turkey aut NATIONALLICENCE 700 1- Celik Erkan Department of Anesthesiology and Reanimation, Trakya University Medical Faculty, 22030, Edirne, Turkey aut NATIONALLICENCE 700 1- Sut Necdet Department of Biostatistics, Trakya University Medical Faculty, Edirne, Turkey aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/12(2015-12-01), 3516-3522 0942-2056 23:12<3516 2015 23 167