caa a22 4500 605457808 CHVBK 20210128100225.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s00167-014-3260-6 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3260-6 Hamstrings anterior cruciate ligament reconstruction with and without platelet rich fibrin matrix [Elektronische Daten] [M. Del Torto, D. Enea, N. Panfoli, G. Filardo, N. Pace, M. Chiusaroli] Purpose: Anterior cruciate ligament (ACL) rupture is the most common complete ligamentous injury in the knee. Many studies explored ACL graft integration and maturation, but only a few assessed the application of platelet rich fibrin matrix (PRFM) as augmentation for ACL reconstruction. The main aim of this study was to test the PRFM augmentation in terms of graft-bone integration and knee stability. The secondary aim was to investigate patient-reported functional status. Methods: Prospective evaluation has been done in two consecutive series of patients who underwent ACL reconstruction with semitendinosus and gracilis (STG) grafts: 14 patients were operated with PRFM augmentation and 14 patients without PRFM augmentation. Objective clinical evaluation (Rolimeter) and MRI evaluation were performed at 1year from surgery. Subjective evaluation (IKDC) was performed pre-operatively and at 6months, 1 and 2years from surgery. Results: A statistically significant difference was not detected between the two groups in terms of MRI and objective clinical evaluation, although PRFM-augmented patients showed a statistically significant higher clinical improvement. Conclusions: The procedure described for PRFM augmentation in ACL STG reconstruction does not improve radiologic graft integration and knee stability after 1year and should not be used by clinicians to this purpose. However, it may result in a short-term improvement of patient-reported knee function, and future research should focus on further developing PRP treatment to optimize ACL clinical outcome. Level of evidence: III. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA), 2014 PRFM nationallicence ACL nationallicence Semitendinosus-gracilis nationallicence MRI nationallicence Platelet-derived growth factors nationallicence Del Torto M. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut Enea D. Department of Orthopaedics, Polytechnic University of Marche, Ancona, Italy aut Panfoli N. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut Filardo G. II Clinic - Biomechanics Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy aut Pace N. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut Chiusaroli M. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/12(2015-12-01), 3614-3622 0942-2056 23:12<3614 2015 23 167 https://doi.org/10.1007/s00167-014-3260-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3260-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Del Torto M. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut NATIONALLICENCE 700 1- Enea D. Department of Orthopaedics, Polytechnic University of Marche, Ancona, Italy aut NATIONALLICENCE 700 1- Panfoli N. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut NATIONALLICENCE 700 1- Filardo G. II Clinic - Biomechanics Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy aut NATIONALLICENCE 700 1- Pace N. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut NATIONALLICENCE 700 1- Chiusaroli M. Department of Orthopaedics and Traumatology, Jesi Civil Hospital, Viale Della Vittoria, 76, Jesi, AN, Italy aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/12(2015-12-01), 3614-3622 0942-2056 23:12<3614 2015 23 167