Evolution of C-reactive protein values in the first month after anterior cruciate ligament reconstruction: reference values
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| 024 | 7 | 0 | |a 10.1007/s00167-013-2702-x |2 doi |
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| 245 | 0 | 0 | |a Evolution of C-reactive protein values in the first month after anterior cruciate ligament reconstruction: reference values |h [Elektronische Daten] |c [Miguel Ruiz-Ibán, Jorge Díaz Heredia, Ignacio Cebreiro Martínez Val, Susana Alonso Güemes, Ricardo Cuéllar Gutiérrez, Sergi Sastre Solsona] |
| 520 | 3 | |a Purpose: C-reactive protein (CRP) is often used as an infection marker in orthopaedic patients and in particular after anterior cruciate ligament (ACL) reconstruction surgery. The aim of this study is to obtain the reference values of CRP during the first month after an ACL reconstruction and to analyse the epidemiological and surgical parameters that affect these values. Methods: One hundred and twenty ACL reconstructions were included. A CRP determination was performed preoperatively and 1, 7, 14, 21 and 28days after surgery. CRP values under 5mg/l were considered to be normal. Results: One patient developed a septic arthritis in the second week postoperatively and was excluded. One hundred and seventeen patients [93 males and 24 females; mean age (standard deviation) 31.6years (7.6)] underwent 119 ACL reconstructions with different techniques and grafts. Preoperative CRP (n=119) was 1.80mg/ml (2.6). Mean values at 1, 7, 14, 21 and 28days were, respectively, 8.5mg/ml (11.6), 10.5mg/ml (17.0), 4.5mg/ml (3.43), 4.4mg/ml (7.59) and 3.4mg/ml (3.03). Multivariate analysis showed that males had postoperative CRP levels 1.7 higher than females (p<0.0001; 95% CI 1.8-2.5); the patients operated by less experienced surgeons had levels 2.5 times higher than those operated by a highly experienced surgeons (p=0.007; 95% CI 1.2-3.4) and that if microfracture of a chondral lesion was associated, the levels increased 1.9 times (p=0.021; 95% CI 1.1-3.4). Conclusions: There are significant variations in CRP levels after ACL reconstruction in half of patients without infectious complications. Males, patients operated by less experienced surgeons and those with chondral lesions treated with microfracture had increased postoperative CRP levels. CRP values up to five times the normal limit are common in the month after an ACL reconstruction and are not necessarily associated with infection, especially in these groups. Level of evidence: Diagnostic study, Level IV. | |
| 540 | |a Springer-Verlag Berlin Heidelberg, 2013 | ||
| 690 | 7 | |a Anterior cruciate ligament |2 nationallicence | |
| 690 | 7 | |a Anterior cruciate ligament reconstruction |2 nationallicence | |
| 690 | 7 | |a C-reactive protein |2 nationallicence | |
| 690 | 7 | |a Infection |2 nationallicence | |
| 700 | 1 | |a Ruiz-Ibán |D Miguel |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | |
| 700 | 1 | |a Díaz Heredia |D Jorge |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | |
| 700 | 1 | |a Cebreiro Martínez Val |D Ignacio |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | |
| 700 | 1 | |a Alonso Güemes |D Susana |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | |
| 700 | 1 | |a Cuéllar Gutiérrez |D Ricardo |u Department of Orthopaedic Surgery, Hospital Universitario Donostia, San Sebastián, Spain |4 aut | |
| 700 | 1 | |a Sastre Solsona |D Sergi |u Department of Orthopaedic Surgery, Hospital Clinic, Barcelona, Spain |4 aut | |
| 773 | 0 | |t Knee Surgery, Sports Traumatology, Arthroscopy |d Springer Berlin Heidelberg |g 23/3(2015-03-01), 763-769 |x 0942-2056 |q 23:3<763 |1 2015 |2 23 |o 167 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00167-013-2702-x |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00167-013-2702-x |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ruiz-Ibán |D Miguel |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Díaz Heredia |D Jorge |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cebreiro Martínez Val |D Ignacio |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Alonso Güemes |D Susana |u Department of Orthopaedic Surgery, Servicio de COT, Hospital Universitario Ramón y Cajal, Cta Colmenar Km 9.100, 28034, Madrid, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cuéllar Gutiérrez |D Ricardo |u Department of Orthopaedic Surgery, Hospital Universitario Donostia, San Sebastián, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sastre Solsona |D Sergi |u Department of Orthopaedic Surgery, Hospital Clinic, Barcelona, Spain |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Knee Surgery, Sports Traumatology, Arthroscopy |d Springer Berlin Heidelberg |g 23/3(2015-03-01), 763-769 |x 0942-2056 |q 23:3<763 |1 2015 |2 23 |o 167 | ||