caa a22 4500 605458685 CHVBK 20210128100230.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00167-013-2787-2 doi (NATIONALLICENCE)springer-10.1007/s00167-013-2787-2 Healing of donor site in bone-tendon-bone ACL reconstruction accelerated with plasma rich in growth factors: a randomized clinical trial [Elektronische Daten] [Roberto Seijas, Marta Rius, Oscar Ares, Montserrat García-Balletbó, Iván Serra, Ramón Cugat] Purpose: To determine whether the use of plasma rich in growth factors accelerates healing of the donor site in bone-tendon-bone anterior cruciate ligament (ACL) reconstruction (patellar graft). The use of the patellar graft presents post-operative problems such as anterior knee pain, which limits its use and leads to preference being taken for alternative grafts. Methods: A double-blind, randomized, clinical trial was performed comparing two groups of patients who underwent ACL reconstruction using patellar tendon graft and comparing the use of plasma rich in growth factors at the donor site after graft harvest in terms of local regeneration by ultrasound assessment. Results: The plasma rich in growth factors group shows earlier donor site regeneration in comparison with the control group (2months earlier), with significant differences in the first 4months of the follow-up. Conclusion: The application of plasma rich in growth factors shows accelerated tissue regeneration processes with respect to the control group. This fact, together with the previously published with similar conclusions, can create a knowledge basis in order to set out new recovery guidelines following ACL reconstruction. Level of evidence: Therapeutic study, Level I. Springer-Verlag Berlin Heidelberg, 2013 Plasma rich in growth factors nationallicence Healing nationallicence Anterior cruciate ligament reconstruction nationallicence Donor site nationallicence Patellar graft nationallicence Seijas Roberto Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut Rius Marta Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut Ares Oscar Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut García-Balletbó Montserrat Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut Serra Iván Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut Cugat Ramón Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/4(2015-04-01), 991-997 0942-2056 23:4<991 2015 23 167 https://doi.org/10.1007/s00167-013-2787-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-013-2787-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Seijas Roberto Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut NATIONALLICENCE 700 1- Rius Marta Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut NATIONALLICENCE 700 1- Ares Oscar Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut NATIONALLICENCE 700 1- García-Balletbó Montserrat Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut NATIONALLICENCE 700 1- Serra Iván Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut NATIONALLICENCE 700 1- Cugat Ramón Orthopaedic Surgery, Artroscopia G.C., Fundación García-Cugat, Hospital Quirón Barcelona, Pza. Alfonso Comín 5-7, 08023, Barcelona, Spain aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/4(2015-04-01), 991-997 0942-2056 23:4<991 2015 23 167