caa a22 4500 605459339 CHVBK 20210128100233.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00167-013-2784-5 doi (NATIONALLICENCE)springer-10.1007/s00167-013-2784-5 Clinical outcomes of platelet rich plasma (PRP) as an adjunct to microfracture surgery in osteochondral lesions of the talus [Elektronische Daten] [Ahmet Guney, Mustafa Akar, Ibrahim Karaman, Mithat Oner, Betul Guney] Purpose: To compare the effect of arthroscopic microfracture surgery alone or in combination with platelet rich plasma (PRP) on functional outcomes in osteochondral lesions of the talus. Methods: A total of 35 patients were included in the study. Control subjects (n=16) received treatment with microfracture surgery alone, while the remaining patients (PRP group, n=19) were also given PRP. After an average follow-up of 16.2months (range 12-24months), patients were assessed using the American Orthopaedic Foot and Ankle Society (AOFAS) scoring system, Foot and Ankle Ability Measure (FAAM), and the visual analogue scale (VAS) for pain. Results: At baseline, AOFAS and FAAM scores were similar in the two groups, whereas pain scores (VAS) were higher in those who were assigned to combined treatment. Despite the latter finding, the combined treatment with PRP resulted in better outcomes in terms of functional scores [AOFAS, 89.2±3.9 vs. 71.0±10.2, (p=0.001); FAAM overall pain domain, 1.0 (1.0-2.0) vs. 2.5 (1.0-4.0), (p=0.04); FAAM 15-min walking domain, 1.0 (1.0-2.0) vs. 2.0 (1.0-4.0) (p=0.001)]; and pain-related scores [VAS, 2.2±0.8 vs. 3.8±1.2, (p=0.001)] as compared to arthroscopic microfracture surgery alone. Conclusions: PRP as an adjunct to arthroscopic microfracture surgery for the treatment of osteochondral lesions of the talus resulted in improved functional score status in the medium-term. Further studies to determine the long-term efficacy of this approach were warranted. Level of evidence: II. Springer-Verlag Berlin Heidelberg, 2013 Osteochondral lesions of talus nationallicence Platelet rich plasma nationallicence Clinical outcome nationallicence Functional outcome nationallicence Arthroscopy nationallicence Microfracture nationallicence Guney Ahmet Department of Orthopedics and Traumatology, Erciyes University Medical Faculty, Kayseri, Turkey aut Akar Mustafa Department of Orthopedics and Traumatology, Osmancik State Hospital, Corum, Turkey aut Karaman Ibrahim Department of Orthopedics and Traumatology, Erciyes University Medical Faculty, Kayseri, Turkey aut Oner Mithat Department of Orthopedics and Traumatology, Erciyes University Medical Faculty, Kayseri, Turkey aut Guney Betul Department of Radiodiagnostics, Kayseri Research and Training Hospital, Kayseri, Turkey aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/8(2015-08-01), 2384-2389 0942-2056 23:8<2384 2015 23 167 https://doi.org/10.1007/s00167-013-2784-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-013-2784-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Guney Ahmet Department of Orthopedics and Traumatology, Erciyes University Medical Faculty, Kayseri, Turkey aut NATIONALLICENCE 700 1- Akar Mustafa Department of Orthopedics and Traumatology, Osmancik State Hospital, Corum, Turkey aut NATIONALLICENCE 700 1- Karaman Ibrahim Department of Orthopedics and Traumatology, Erciyes University Medical Faculty, Kayseri, Turkey aut NATIONALLICENCE 700 1- Oner Mithat Department of Orthopedics and Traumatology, Erciyes University Medical Faculty, Kayseri, Turkey aut NATIONALLICENCE 700 1- Guney Betul Department of Radiodiagnostics, Kayseri Research and Training Hospital, Kayseri, Turkey aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/8(2015-08-01), 2384-2389 0942-2056 23:8<2384 2015 23 167