caa a22 4500 605459371 CHVBK 20210128100233.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00167-014-3049-7 doi (NATIONALLICENCE)springer-10.1007/s00167-014-3049-7 The efficacy of steroid injection in total knee or hip arthroplasty [Elektronische Daten] [Zhaohui Cui, Xue Liu, Yuanjun Teng, Jin Jiang, Jing Wang, Yayi Xia] Purpose: A systematic review and meta-analysis based on randomized controlled trials (RCTs) was conducted to evaluate the efficacy and safety of steroid injection in total knee or hip arthroplasty (TKA/THA). Methods: A systematical electronic search identified the relevant RCTs in the databases of PubMed, EMBASE, MEDLINE and Cochrane Central Register of Controlled Trials. Two reviewers independently completed data collection and assessment of methodological quality. Meta-analysis was performed for the outcomes of visual analogue pain score, range of motion (ROM), postoperative nausea and vomiting (PONV), morphine consumption, length of stay and complications. Results: A total of 863 participants were enrolled. Patients who received steroid injection had a significant reduction in the incidence of PONV and improvement in short-term pain score, and ROM (p<0.05). Regarding morphine consumption and hospitalization time, the steroid group showed a significant reduction in TKA but no statistically significant difference in THA. In addition, there were no significant differences in complications (n.s.). Conclusions: The current evidence suggests that steroid injection in TKA/THA provides short-term advantages in pain relief and antiemetic effects. The optimal dose and long-term effects of steroid injection still require numerous studies. Level of evidence: II. Springer-Verlag Berlin Heidelberg, 2014 Total knee arthroplasty nationallicence Total hip arthroplasty nationallicence Steroid injection nationallicence Randomized controlled trial nationallicence Cui Zhaohui Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut Liu Xue Department of Oncology, The First Hospital of Jilin University, Xinmin Street, Chaoyang District, 130000, Changchun City, Jilin Province, China aut Teng Yuanjun Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut Jiang Jin Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut Wang Jing Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut Xia Yayi Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/8(2015-08-01), 2306-2314 0942-2056 23:8<2306 2015 23 167 https://doi.org/10.1007/s00167-014-3049-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00167-014-3049-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cui Zhaohui Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut NATIONALLICENCE 700 1- Liu Xue Department of Oncology, The First Hospital of Jilin University, Xinmin Street, Chaoyang District, 130000, Changchun City, Jilin Province, China aut NATIONALLICENCE 700 1- Teng Yuanjun Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut NATIONALLICENCE 700 1- Jiang Jin Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut NATIONALLICENCE 700 1- Wang Jing Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut NATIONALLICENCE 700 1- Xia Yayi Orthopaedics Key Laboratory of Gansu Province, The Second Hospital of Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, China aut NATIONALLICENCE 773 0- Knee Surgery, Sports Traumatology, Arthroscopy Springer Berlin Heidelberg 23/8(2015-08-01), 2306-2314 0942-2056 23:8<2306 2015 23 167